A New In Vivo Screening Paradigm to Accelerate Antimalarial Drug Discovery

The emergence of resistance to available antimalarials requires the urgent development of new medicines. The recent disclosure of several thousand compounds active in vitro against the erythrocyte stage of Plasmodium falciparum has been a major breakthrough, though converting these hits into new med...

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Hlavní autoři: Jiménez-Díaz, María Belén, Viera, Sara, Ibáñez, Javier, Mulet, Teresa, Magán-Marchal, Noemí, Garuti, Helen, Gómez, Vanessa, Cortés-Gil, Lorena, Martínez, Antonio, Ferrer, Santiago, Fraile, María Teresa, Calderón, Félix, Fernández, Esther, Shultz, Leonard D., Leroy, Didier, Wilson, David M., García-Bustos, José Francisco, Gamo, Francisco Javier, Angulo-Barturen, Iñigo
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692522/
https://ncbi.nlm.nih.gov/pubmed/23825598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066967
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