Intracellular NAD(+) depletion induces autophagic death in multiple myeloma cells

Autor Cea, Michele, Cagnetta, Antonia, Patrone, Franco, Nencioni, Alessio, Gobbi, Marco, Anderson, Kenneth C.
Vydáno 2013

New Insights into the Treatment of Multiple Myeloma with Histone Deacetylase Inhibitors

Autor Cea, Michele, Cagnetta, Antonia, Gobbi, Marco, Patrone, Franco, Richardson, Paul G., Hideshima, Teru, Anderson, Kenneth C.
Vydáno 2013

Mechanisms and Clinical Applications of Genome Instability in Multiple Myeloma

Autor Cagnetta, Antonia, Lovera, Davide, Grasso, Raffaella, Colombo, Nicoletta, Canepa, Letizia, Ballerini, Filippo, Calvio, Marino, Miglino, Maurizio, Gobbi, Marco, Lemoli, Roberto, Cea, Michele
Vydáno v Biomed Res Int (2015)

Intracellular NAD(+) depletion enhances bortezomib-induced anti-myeloma activity

Autor Cagnetta, Antonia, Cea, Michele, Calimeri, Teresa, Acharya, Chirag, Fulciniti, Mariateresa, Tai, Yu-Tzu, Hideshima, Teru, Chauhan, Dharminder, Zhong, Mike Y., Patrone, Franco, Nencioni, Alessio, Gobbi, Marco, Richardson, Paul, Munshi, Nikhil, Anderson, Kenneth C.
Vydáno 2013

APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment

Autor Tai, Yu-Tzu, Acharya, Chirag, An, Gang, Moschetta, Michele, Zhong, Mike Y., Feng, Xiaoyan, Cea, Michele, Cagnetta, Antonia, Wen, Kenneth, van Eenennaam, Hans, van Elsas, Andrea, Qiu, Lugui, Richardson, Paul, Munshi, Nikhil, Anderson, Kenneth C.
Vydáno v Blood (2016)

Targeting NAD(+) salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition

Autor Cea, Michele, Cagnetta, Antonia, Fulciniti, Mariateresa, Tai, Yu-Tzu, Hideshima, Teru, Chauhan, Dharminder, Roccaro, Aldo, Sacco, Antonio, Calimeri, Teresa, Cottini, Francesca, Jakubikova, Jana, Kong, Sun-Young, Patrone, Franco, Nencioni, Alessio, Gobbi, Marco, Richardson, Paul, Munshi, Nikhil, Anderson, Kenneth C.
Vydáno 2012

Novel anti–B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma

Autor Tai, Yu-Tzu, Mayes, Patrick A., Acharya, Chirag, Zhong, Mike Y., Cea, Michele, Cagnetta, Antonia, Craigen, Jenny, Yates, John, Gliddon, Louise, Fieles, William, Hoang, Bao, Tunstead, James, Christie, Amanda L., Kung, Andrew L., Richardson, Paul, Munshi, Nikhil C., Anderson, Kenneth C.
Vydáno 2014

The Non-Coding RNA Landscape of Plasma Cell Dyscrasias

Autor Morelli, Eugenio, Gullà, Annamaria, Rocca, Roberta, Federico, Cinzia, Raimondi, Lavinia, Malvestiti, Stefano, Agosti, Valter, Rossi, Marco, Costa, Giosuè, Giavaresi, Gianluca, Azab, Abdel Kareem, Cagnetta, Antonia, Cea, Michele, Tagliaferri, Pierosandro, Neri, Antonino, Munshi, Nikhil C., Viglietto, Giuseppe, Tassone, Pierfrancesco, Amodio, Nicola
Vydáno v Cancers (Basel) (2020)

Amino acid depletion triggered by ʟ-asparaginase sensitizes MM cells to carfilzomib by inducing mitochondria ROS-mediated cell death

Autor Soncini, Debora, Minetto, Paola, Martinuzzi, Claudia, Becherini, Pamela, Fenu, Valeria, Guolo, Fabio, Todoerti, Katia, Calice, Giovanni, Contini, Paola, Miglino, Maurizio, Rivoli, Giulia, Aquino, Sara, Dominietto, Alida, Cagnetta, Antonia, Passalacqua, Mario, Bruzzone, Santina, Nencioni, Alessio, Zucchetti, Massimo, Ceruti, Tommaso, Neri, Antonino, Lemoli, Roberto M., Cea, Michele
Vydáno v Blood Adv (2020)

Nicotinamide Phosphoribosyltransferase Promotes Epithelial-to-Mesenchymal Transition as a Soluble Factor Independent of Its Enzymatic Activity

Autor Soncini, Debora, Caffa, Irene, Zoppoli, Gabriele, Cea, Michele, Cagnetta, Antonia, Passalacqua, Mario, Mastracci, Luca, Boero, Silvia, Montecucco, Fabrizio, Sociali, Giovanna, Lasigliè, Denise, Damonte, Patrizia, Grozio, Alessia, Mannino, Elena, Poggi, Alessandro, D'Agostino, Vito G., Monacelli, Fiammetta, Provenzani, Alessandro, Odetti, Patrizio, Ballestrero, Alberto, Bruzzone, Santina, Nencioni, Alessio
Vydáno v J Biol Chem (2014)

Dual NAMPT and BTK Targeting Leads to Synergistic Killing of Waldenstrom's Macroglobulinemia Cells Regardless of MYD88 and CXCR4 Somatic Mutations Status

Autor Cea, Michele, Cagnetta, Antonia, Acharya, Chirag, Acharya, Prakrati, Tai, Yu-Tzu, Yang, Guang, Lovera, Davide, Soncini, Debora, Miglino, Maurizio, Fraternali-Orcioni, Giulio, Mastracci, Luca, Nencioni, Alessio, Montecucco, Fabrizio, Ballestrero, Alberto, Hideshima, Teru, Chauhan, Dharminder, Gobbi, Marco, Lemoli, Roberto M., Munshi, Nikhil, Treon, Steven P., Anderson, Kenneth C.
Vydáno v Clin Cancer Res (2016)

Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells’ vulnerability to DNA-damaging agents

Autor Cagnetta, Antonia, Soncini, Debora, Orecchioni, Stefania, Talarico, Giovanna, Minetto, Paola, Guolo, Fabio, Retali, Veronica, Colombo, Nicoletta, Carminati, Enrico, Clavio, Marino, Miglino, Maurizio, Bergamaschi, Micaela, Nahimana, Aimable, Duchosal, Michel, Todoerti, Katia, Neri, Antonino, Passalacqua, Mario, Bruzzone, Santina, Nencioni, Alessio, Bertolini, Francesco, Gobbi, Marco, Lemoli, Roberto M., Cea, Michele
Vydáno v Haematologica (2018)

Synergistic Interactions between HDAC and Sirtuin Inhibitors in Human Leukemia Cells

Autor Cea, Michele, Soncini, Debora, Fruscione, Floriana, Raffaghello, Lizzia, Garuti, Anna, Emionite, Laura, Moran, Eva, Magnone, Mirko, Zoppoli, Gabriele, Reverberi, Daniele, Caffa, Irene, Salis, Annalisa, Cagnetta, Antonia, Bergamaschi, Micaela, Casciaro, Salvatore, Pierri, Ivana, Damonte, Gianluca, Ansaldi, Filippo, Gobbi, Marco, Pistoia, Vito, Ballestrero, Alberto, Patrone, Franco, Bruzzone, Santina, Nencioni, Alessio
Vydáno 2011

Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells

Autor Cea, Michele, Cagnetta, Antonia, Adamia, Sophia, Acharya, Chirag, Tai, Yu-Tzu, Fulciniti, Mariateresa, Ohguchi, Hiroto, Munshi, Aditya, Acharya, Prakrati, Bhasin, Manoj K., Zhong, Lei, Carrasco, Ruben, Monacelli, Fiammetta, Ballestrero, Alberto, Richardson, Paul, Gobbi, Marco, Lemoli, Roberto M., Munshi, Nikhil, Hideshima, Teru, Nencioni, Alessio, Chauhan, Dharminder, Anderson, Kenneth C.
Vydáno v Blood (2016)

The new small tyrosine kinase inhibitor ARQ531 targets acute myeloid leukemia cells by disrupting multiple tumor-addicted programs

Autor Soncini, Debora, Orecchioni, Stefania, Ruberti, Samantha, Minetto, Paola, Martinuzzi, Claudia, Agnelli, Luca, Todoerti, Katia, Cagnetta, Antonia, Miglino, Maurizio, Clavio, Marino, Contini, Paola, Varaldo, Riccardo, Bergamaschi, Micaela, Guolo, Fabio, Passalacqua, Mario, Nencioni, Alessio, Monacelli, Fiammetta, Gobbi, Marco, Neri, Antonino, Abbadessa, Giovanni, Eathiraj, Sudharshan, Schwartz, Brian, Bertolini, Francesco, Lemoli, Roberto M., Cea, Michele
Vydáno v Haematologica (2019)

Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma

Autor Tai, Yu-Tzu, Chang, Betty Y., Kong, Sun-Young, Fulciniti, Mariateresa, Yang, Guang, Calle, Yolanda, Hu, Yiguo, Lin, Jianhong, Zhao, Jian-Jun, Cagnetta, Antonia, Cea, Michele, Sellitto, Michael A., Zhong, Mike Y., Wang, Qiuju, Acharya, Chirag, Carrasco, Daniel R., Buggy, Joseph J., Elias, Laurence, Treon, Steven P., Matsui, William, Richardson, Paul, Munshi, Nikhil C., Anderson, Kenneth C.
Vydáno 2012