Mechanisms and Clinical Applications of Genome Instability in Multiple Myeloma

Ongoing genomic instability represents a hallmark of multiple myeloma (MM) cells, which manifests largely as whole chromosome- or translocation-based aneuploidy. Importantly, although it supports tumorigenesis, progression and, response to treatment in MM patients, it remains one of the least unders...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Cagnetta, Antonia, Lovera, Davide, Grasso, Raffaella, Colombo, Nicoletta, Canepa, Letizia, Ballerini, Filippo, Calvio, Marino, Miglino, Maurizio, Gobbi, Marco, Lemoli, Roberto, Cea, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633548/
https://ncbi.nlm.nih.gov/pubmed/26579543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/943096
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