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Intracellular NAD(+) depletion induces autophagic death in multiple myeloma cells

Multiple myeloma (MM) is a clonal B-cell malignancy characterized by the proliferation of plasma cells in the bone marrow. Despite recent therapeutic advances, MM remains an incurable disease. Therefore, research has focused on defining new aspects in MM biology that can be therapeutically targeted....

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Autors principals: Cea, Michele, Cagnetta, Antonia, Patrone, Franco, Nencioni, Alessio, Gobbi, Marco, Anderson, Kenneth C.
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590260/
https://ncbi.nlm.nih.gov/pubmed/23221771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22866
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