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Protector turns predator: Autophagic death via selective degradation of KRAS
Therapy-induced autophagy is recognized as a critical determinant of treatment outcome in cancer patients, primarily as a factor underlying drug resistance. However, recent investigations point toward a context-dependent, death-inducing role for autophagy, the mechanism of which remains largely unkn...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Landes Bioscience
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4026028/ https://ncbi.nlm.nih.gov/pubmed/24121562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.25837 |
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