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Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells
Multiple myeloma (MM) is characterized by a highly unstable genome, with aneuploidy observed in nearly all patients. The mechanism causing this karyotypic instability is largely unknown, but recent observations have correlated these abnormalities with dysfunctional DNA damage response. Here, we show...
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| Vydáno v: | Blood |
|---|---|
| Hlavní autoři: | , , , , , , , , , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4778164/ https://ncbi.nlm.nih.gov/pubmed/26675349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-06-649970 |
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