In Vitro–In Vivo Inaccuracy: The CYP3A4 Anomaly

per Bowman, Christine M., Benet, Leslie Z.
Publicat a Drug Metab Dispos (2019)

Interlaboratory Variability in Human Hepatocyte Intrinsic Clearance Values and Trends with Physicochemical Properties

per Bowman, Christine M., Benet, Leslie Z.
Publicat a Pharm Res (2019)

In vitro-in vivo extrapolation and hepatic clearance dependent underprediction

per Bowman, Christine M., Benet, Leslie Z.
Publicat a J Pharm Sci (2019)

Synthesis and evaluation of N(8)-acetylspermidine analogues as inhibitors of bacterial acetylpolyamine amidohydrolase

per Decroos, Christophe, Bowman, Christine M., Christianson, David W.
Publicat 2013

The Presence of a Transporter-Induced Protein Binding Shift: A New Explanation for Protein-Facilitated Uptake and Improvement for In Vitro-In Vivo Extrapolation

per Bowman, Christine M., Okochi, Hideaki, Benet, Leslie Z.
Publicat a Drug Metab Dispos (2019)

How Transporters Have Changed Basic Pharmacokinetic Understanding

per Benet, Leslie Z., Bowman, Christine M., Sodhi, Jasleen K.
Publicat a AAPS J (2019)

Examination of Physiologically‐Based Pharmacokinetic Models of Rosuvastatin

per Bowman, Christine M., Ma, Fang, Mao, Jialin, Chen, Yuan
Publicat a CPT Pharmacometrics Syst Pharmacol (2020)

The Extended Clearance Concept Following Oral and Intravenous Dosing: Theory and Critical Analyses

per Benet, Leslie Z., Bowman, Christine M., Liu, Shufang, Sodhi, Jasleen K.
Publicat a Pharm Res (2018)

Energetically Unfavorable Amide Conformations for N6-Acetyllysine Side Chains in Refined Protein Structures

per Genshaft, Alexander, Moser, Joe-Ann S., D'Antonio, Edward L., Bowman, Christine M., Christianson, David W.
Publicat 2013

Understanding drug-drug interaction and pharmacogenomic changes in pharmacokinetics for metabolized drugs

per Benet, Leslie Z., Bowman, Christine M., Koleske, Megan L., Rinaldi, Capria L., Sodhi, Jasleen K.
Publicat a J Pharmacokinet Pharmacodyn (2019)

Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders

per Decroos, Christophe, Bowman, Christine M., Moser, Joe-Ann S., Christianson, Karen E., Deardorff, Matthew A., Christianson, David W.
Publicat 2014

Biochemical and Structural Characterization of HDAC8 Mutants Associated with Cornelia de Lange Syndrome Spectrum Disorders

per Decroos, Christophe, Christianson, Nicolas H., Gullett, Laura E., Bowman, Christine M., Christianson, Karen E., Deardorff, Matthew A., Christianson, David W.
Publicat a Biochemistry (2015)

General Base-General Acid Catalysis in Human Histone Deacetylase 8

per Lucy Gantt, Sister M., Decroos, Christophe, Lee, Matthew S., Gullett, Laura E., Bowman, Christine M., Christianson, David W., Fierke, Carol A.
Publicat a Biochemistry (2016)

Loss-of-function HDAC8 mutations cause a phenotypic spectrum of Cornelia de Lange syndrome-like features, ocular hypertelorism, large fontanelle and X-linked inheritance

per Kaiser, Frank J., Ansari, Morad, Braunholz, Diana, Concepción Gil-Rodríguez, María, Decroos, Christophe, Wilde, Jonathan J., Fincher, Christopher T., Kaur, Maninder, Bando, Masashige, Amor, David J., Atwal, Paldeep S., Bahlo, Melanie, Bowman, Christine M., Bradley, Jacquelyn J., Brunner, Han G., Clark, Dinah, Del Campo, Miguel, Di Donato, Nataliya, Diakumis, Peter, Dubbs, Holly, Dyment, David A., Eckhold, Juliane, Ernst, Sarah, Ferreira, Jose C., Francey, Lauren J., Gehlken, Ulrike, Guillén-Navarro, Encarna, Gyftodimou, Yolanda, Hall, Bryan D., Hennekam, Raoul, Hudgins, Louanne, Hullings, Melanie, Hunter, Jennifer M., Yntema, Helger, Innes, A. Micheil, Kline, Antonie D., Krumina, Zita, Lee, Hane, Leppig, Kathleen, Lynch, Sally Ann, Mallozzi, Mark B., Mannini, Linda, Mckee, Shane, Mehta, Sarju G., Micule, Ieva, Mohammed, Shehla, Moran, Ellen, Mortier, Geert R., Moser, Joe-Ann S., Noon, Sarah E., Nozaki, Naohito, Nunes, Luis, Pappas, John G., Penney, Lynette S., Pérez-Aytés, Antonio, Petersen, Michael B., Puisac, Beatriz, Revencu, Nicole, Roeder, Elizabeth, Saitta, Sulagna, Scheuerle, Angela E., Schindeler, Karen L., Siu, Victoria M., Stark, Zornitza, Strom, Samuel P., Thiese, Heidi, Vater, Inga, Willems, Patrick, Williamson, Kathleen, Wilson, Louise C., Hakonarson, Hakon, Quintero-Rivera, Fabiola, Wierzba, Jolanta, Musio, Antonio, Gillessen-Kaesbach, Gabriele, Ramos, Feliciano J., Jackson, Laird G., Shirahige, Katsuhiko, Pié, Juan, Christianson, David W., Krantz, Ian D., Fitzpatrick, David R., Deardorff, Matthew A.
Publicat 2014