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Synthesis and evaluation of N(8)-acetylspermidine analogues as inhibitors of bacterial acetylpolyamine amidohydrolase
Polyamines are small essential polycations involved in many biological processes. Enzymes of polyamine metabolism have been extensively studied and are attractive drug targets. Nevertheless, the reversible acetylation of polyamines remains poorly understood. Although eukaryotic N(8)-acetylspermidine...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3715397/ https://ncbi.nlm.nih.gov/pubmed/23790721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.05.045 |
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