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Synthesis and evaluation of N(8)-acetylspermidine analogues as inhibitors of bacterial acetylpolyamine amidohydrolase
Polyamines are small essential polycations involved in many biological processes. Enzymes of polyamine metabolism have been extensively studied and are attractive drug targets. Nevertheless, the reversible acetylation of polyamines remains poorly understood. Although eukaryotic N(8)-acetylspermidine...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3715397/ https://ncbi.nlm.nih.gov/pubmed/23790721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.05.045 |
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