Harnessing poxviral know-how for anti-cytokine therapies

Por Bowie, Andrew G.
Publicado no J Biol Chem (2019)

Poxviral Protein A46 Antagonizes Toll-like Receptor 4 Signaling by Targeting BB Loop Motifs in Toll-IL-1 Receptor Adaptor Proteins to Disrupt Receptor:Adaptor Interactions

Por Stack, Julianne, Bowie, Andrew G.
Publicado em 2012

Innate immune detection of microbial nucleic acids

Por Gürtler, Claudia, Bowie, Andrew G.
Publicado em 2013

Innate Immune Recognition of DNA: a recent history

Por Dempsey, Alan, Bowie, Andrew G
Publicado no Virology (2015)

Role of Non-degradative Ubiquitination in Interleukin-1 and Toll-like Receptor Signaling

Por Keating, Sinéad E., Bowie, Andrew G.
Publicado em 2009

Immune sensing of DNA

Por Paludan, Søren R., Bowie, Andrew G.
Publicado em 2013

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKɛ-mediated IRF activation

Por Schröder, Martina, Baran, Marcin, Bowie, Andrew G
Publicado em 2008

Poxviral protein E3–altered cytokine production reveals that DExD/H-box helicase 9 controls Toll-like receptor–stimulated immune responses

Por Dempsey, Alan, Keating, Sinead E., Carty, Michael, Bowie, Andrew G.
Publicado no J Biol Chem (2018)

Human Interleukin-1 Receptor-associated Kinase-2 Is Essential for Toll-like Receptor-mediated Transcriptional and Post-transcriptional Regulation of Tumor Necrosis Factor α

Por Flannery, Sinead M., Keating, Sinead E., Szymak, Joanna, Bowie, Andrew G.
Publicado em 2011

Recognition of herpesviruses by the innate immune system

Por Paludan, Søren R., Bowie, Andrew G., Horan, Kristy A., Fitzgerald, Katherine A.
Publicado em 2011

Poxvirus Protein MC132 from Molluscum Contagiosum Virus Inhibits NF-κB Activation by Targeting p65 for Degradation

Por Brady, Gareth, Haas, Darya A., Farrell, Paul J., Pichlmair, Andreas, Bowie, Andrew G.
Publicado no J Virol (2015)

Molluscum Contagiosum Virus Protein MC005 Inhibits NF-κB Activation by Targeting NEMO-Regulated IκB Kinase Activation

Por Brady, Gareth, Haas, Darya A., Farrell, Paul J., Pichlmair, Andreas, Bowie, Andrew G.
Publicado no J Virol (2017)

The Endocannabinoid, Anandamide, Augments Notch-1 Signaling in Cultured Cortical Neurons Exposed to Amyloid-β and in the Cortex of Aged Rats

Por Tanveer, Riffat, Gowran, Aoife, Noonan, Janis, Keating, Sinead E., Bowie, Andrew G., Campbell, Veronica A.
Publicado em 2012

SARM regulates CCL5 production in macrophages by promoting the recruitment of transcription factors and RNA polymerase II to the Ccl5 promoter

Por Gürtler, Claudia, Carty, Michael, Kearney, Jay, Schattgen, Stefan A., Ding, Aihao, Fitzgerald, Katherine A., Bowie, Andrew G.
Publicado em 2014

DNA sensors are expressed in astrocytes and microglia in vitro and are upregulated during gliosis in neurodegenerative disease

Por Cox, Donal J., Field, Robert H., Williams, David G., Baran, Marcin, Bowie, Andrew G., Cunningham, Colm, Dunne, Aisling
Publicado no Glia (2015)

Neuronal toll-like receptor 4 signaling induces brain endothelial activation and neutrophil transmigration in vitro

Por Leow-Dyke, Sophie, Allen, Charlotte, Denes, Adam, Nilsson, Olov, Maysami, Samaneh, Bowie, Andrew G, Rothwell, Nancy J, Pinteaux, Emmanuel
Publicado em 2012

Activation of Innate Defense against a Paramyxovirus Is Mediated by RIG-I and TLR7 and TLR8 in a Cell-Type-Specific Manner

Por Melchjorsen, Jesper, Jensen, Søren B., Malmgaard, Lene, Rasmussen, Simon B., Weber, Friedemann, Bowie, Andrew G., Matikainen, Sampsa, Paludan, Søren R.
Publicado em 2005

Poxviral Protein A52 Stimulates p38 Mitogen-activated Protein Kinase (MAPK) Activation by Causing Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) Self-association Leadin...

Por Stack, Julianne, Hurst, Tara P., Flannery, Sinead M., Brennan, Kiva, Rupp, Sebastian, Oda, Shun-ichiro, Khan, Amir R., Bowie, Andrew G.
Publicado em 2013

Alum Activates the Bovine NLRP3 Inflammasome

Por Harte, Ciaran, Gorman, Aoife L., McCluskey, S., Carty, Michael, Bowie, Andrew G., Scott, C. J., Meade, Kieran G., Lavelle, Ed C.
Publicado no Front Immunol (2017)

Vaccinia Virus Protein C6 Is a Virulence Factor that Binds TBK-1 Adaptor Proteins and Inhibits Activation of IRF3 and IRF7

Por Unterholzner, Leonie, Sumner, Rebecca P., Baran, Marcin, Ren, Hongwei, Mansur, Daniel S., Bourke, Nollaig M., Randow, Felix, Smith, Geoffrey L., Bowie, Andrew G.
Publicado em 2011