Activation of Innate Defense against a Paramyxovirus Is Mediated by RIG-I and TLR7 and TLR8 in a Cell-Type-Specific Manner

Recognition of pathogens by the innate immune system is mediated by pattern recognition receptors (PRRs), which recognize specific molecular structures of the infectious agents and subsequently trigger expression of genes involved in host defense. Toll-like receptors (TLRs) represent a well-characte...

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Autors principals: Melchjorsen, Jesper, Jensen, Søren B., Malmgaard, Lene, Rasmussen, Simon B., Weber, Friedemann, Bowie, Andrew G., Matikainen, Sampsa, Paludan, Søren R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1235860/
https://ncbi.nlm.nih.gov/pubmed/16188996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.20.12944-12951.2005
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