Activation of Innate Defense against a Paramyxovirus Is Mediated by RIG-I and TLR7 and TLR8 in a Cell-Type-Specific Manner

Recognition of pathogens by the innate immune system is mediated by pattern recognition receptors (PRRs), which recognize specific molecular structures of the infectious agents and subsequently trigger expression of genes involved in host defense. Toll-like receptors (TLRs) represent a well-characte...

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Detalhes bibliográficos
Main Authors: Melchjorsen, Jesper, Jensen, Søren B., Malmgaard, Lene, Rasmussen, Simon B., Weber, Friedemann, Bowie, Andrew G., Matikainen, Sampsa, Paludan, Søren R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1235860/
https://ncbi.nlm.nih.gov/pubmed/16188996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.20.12944-12951.2005
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