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Poxviral protein E3–altered cytokine production reveals that DExD/H-box helicase 9 controls Toll-like receptor–stimulated immune responses

Host pattern recognition receptors (PRRs) such as Toll-like receptors (TLRs) detect viruses and other pathogens, inducing production of cytokines that cause inflammation and mobilize cells to control infection. Vaccinia virus (VACV) encodes proteins that antagonize these host innate immune responses...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Dempsey, Alan, Keating, Sinead E., Carty, Michael, Bowie, Andrew G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166711/
https://ncbi.nlm.nih.gov/pubmed/30111593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005089
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