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Immune sensing of DNA

Although it has been appreciated for some years that cytosolic DNA is immune-stimulatory, it is only in the past five years that the molecular basis of DNA sensing by the innate immune system has begun to be revealed. In particular it has been described how DNA induces type I interferon, central in...

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Autori principali: Paludan, Søren R., Bowie, Andrew G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683625/
https://ncbi.nlm.nih.gov/pubmed/23706668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.05.004
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