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Innate immune detection of microbial nucleic acids
Detection of pathogen-derived nucleic acids by pattern recognition receptors (PRRs) is essential for the host to mount an appropriate immune response, which for viruses involves the induction of type I interferons (IFNs). On the other hand, inappropriate activation of PRRs by self nucleic acids can...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735846/ https://ncbi.nlm.nih.gov/pubmed/23726320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tim.2013.04.004 |
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