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Innate immune detection of microbial nucleic acids

Detection of pathogen-derived nucleic acids by pattern recognition receptors (PRRs) is essential for the host to mount an appropriate immune response, which for viruses involves the induction of type I interferons (IFNs). On the other hand, inappropriate activation of PRRs by self nucleic acids can...

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Bibliografski detalji
Glavni autori: Gürtler, Claudia, Bowie, Andrew G.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735846/
https://ncbi.nlm.nih.gov/pubmed/23726320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tim.2013.04.004
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