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Innate immune responses triggered by nucleic acids inspire the design of immunomodulatory nucleic acid nanoparticles (NANPs)
The unknown immune stimulation by nucleic acid nanoparticles (NANPs) has become one of the major impediments to a broad spectrum of clinical developments of this novel technology. Having evolved to defend against bacterial and viral nucleic acids, mammalian cells have established patterns of recogni...
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| Publicado en: | Curr Opin Biotechnol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7246180/ https://ncbi.nlm.nih.gov/pubmed/31778882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.copbio.2019.10.011 |
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