A cationic amphiphilic co-polymer as a carrier of nucleic acid nanoparticles (NANPs) for controlled gene silencing, immunostimulation, and biodistribution

Programmable nucleic acid nanoparticles (NANPs) provide controlled coordination of therapeutic nucleic acids (TNAs) and other biological functionalities. Beyond multivalence, recent reports demonstrate that NANP technology can also elicit a specific immune response, adding another layer of customiza...

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Detalhes bibliográficos
Publicado no:Nanomedicine
Main Authors: Halman, Justin R., Kim, Ki-Taek, Gwak, So-Jung, Pace, Richard, Johnson, Morgan Brittany, Chandler, Morgan R., Rackley, Lauren, Viard, Mathias, Marriott, Ian, Lee, Jeoung Soo, Afonin, Kirill A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942546/
https://ncbi.nlm.nih.gov/pubmed/31669854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2019.102094
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