A cationic amphiphilic co-polymer as a carrier of nucleic acid nanoparticles (NANPs) for controlled gene silencing, immunostimulation, and biodistribution

Programmable nucleic acid nanoparticles (NANPs) provide controlled coordination of therapeutic nucleic acids (TNAs) and other biological functionalities. Beyond multivalence, recent reports demonstrate that NANP technology can also elicit a specific immune response, adding another layer of customiza...

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Pubblicato in:Nanomedicine
Autori principali: Halman, Justin R., Kim, Ki-Taek, Gwak, So-Jung, Pace, Richard, Johnson, Morgan Brittany, Chandler, Morgan R., Rackley, Lauren, Viard, Mathias, Marriott, Ian, Lee, Jeoung Soo, Afonin, Kirill A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942546/
https://ncbi.nlm.nih.gov/pubmed/31669854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2019.102094
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