A cationic amphiphilic co-polymer as a carrier of nucleic acid nanoparticles (NANPs) for controlled gene silencing, immunostimulation, and biodistribution

Programmable nucleic acid nanoparticles (NANPs) provide controlled coordination of therapeutic nucleic acids (TNAs) and other biological functionalities. Beyond multivalence, recent reports demonstrate that NANP technology can also elicit a specific immune response, adding another layer of customiza...

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Détails bibliographiques
Publié dans:Nanomedicine
Auteurs principaux: Halman, Justin R., Kim, Ki-Taek, Gwak, So-Jung, Pace, Richard, Johnson, Morgan Brittany, Chandler, Morgan R., Rackley, Lauren, Viard, Mathias, Marriott, Ian, Lee, Jeoung Soo, Afonin, Kirill A.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942546/
https://ncbi.nlm.nih.gov/pubmed/31669854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2019.102094
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