A cationic amphiphilic co-polymer as a carrier of nucleic acid nanoparticles (NANPs) for controlled gene silencing, immunostimulation, and biodistribution

Programmable nucleic acid nanoparticles (NANPs) provide controlled coordination of therapeutic nucleic acids (TNAs) and other biological functionalities. Beyond multivalence, recent reports demonstrate that NANP technology can also elicit a specific immune response, adding another layer of customiza...

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Publicado en:Nanomedicine
Autores principales: Halman, Justin R., Kim, Ki-Taek, Gwak, So-Jung, Pace, Richard, Johnson, Morgan Brittany, Chandler, Morgan R., Rackley, Lauren, Viard, Mathias, Marriott, Ian, Lee, Jeoung Soo, Afonin, Kirill A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942546/
https://ncbi.nlm.nih.gov/pubmed/31669854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2019.102094
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