Identifying Cancer-Relevant Mutations in the DLC START Domain Using Evolutionary and Structure-Function Analyses

Yazar: Holub, Ashton S., Bouley, Renee A., Petreaca, Ruben C., Husbands, Aman Y.
Yayımlandı Int J Mol Sci (2020)

Exploration of mild copper-mediated coupling of organotrifluoroborates in the synthesis of thiirane-based inhibitors of matrix metalloproteinases

Yazar: Testero, Sebastian A., Bouley, Renee, Fisher, Jed F., Chang, Mayland, Mobashery, Shahriar
Baskı/Yayın Bilgisi 2010

Structural basis of lysosomal phospholipase A(2) inhibition by Zn(2+)

Yazar: Bouley, Renee A., Hinkovska-Galcheva, Vania, Shayman, James A., Tesmer, John J. G.
Yayımlandı Biochemistry (2019)

Utilizing a Structure-Based Docking Approach to Develop Potent G Protein-Coupled Receptor Kinase (GRK) 2 and 5 Inhibitors

Yazar: Waldschmidt, Helen V., Bouley, Renee, Kirchhoff, Paul D., Lee, Pil, Tesmer, John J. G., Larsen, Scott D.
Yayımlandı Bioorg Med Chem Lett (2018)

Synthesis and Evaluation of 1,2,4-Triazolo[1,5-a]pyrimidines as Antibacterial Agents Against Enterococcus faecium

Yazar: Wang, Huan, Lee, Mijoon, Peng, Zhihong, Blázquez, Blas, Lastochkin, Elena, Kumarasiri, Malika, Bouley, Renee, Chang, Mayland, Mobashery, Shahriar
Yayımlandı J Med Chem (2015)

Generation of Highly Selective, Potent, and Covalent G Protein-Coupled Receptor Kinase 5 Inhibitors

Yazar: Rowlands, Rachel A., Chen, Qiuyan, Bouley, Renee A., Avramova, Larisa V., Tesmer, John J. G., White, Andrew D.
Yayımlandı J Med Chem (2021)

Conformational dynamics in penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus, allosteric communication network and enablement of catalysis

Yazar: Mahasenan, Kiran V., Molina, Rafael, Bouley, Renee, Batuecas, María T., Fisher, Jed F., Hermoso, Juan A., Chang, Mayland, Mobashery, Shahriar
Yayımlandı J Am Chem Soc (2017)

Determinants of pH profile and acyl chain selectivity in lysosomal phospholipase A(2)

Yazar: Hinkovska-Galcheva, Vania, Kelly, Robert, Manthei, Kelly A., Bouley, Renee, Yuan, Wenmin, Schwendeman, Anna, Tesmer, John J. G., Shayman, James A.
Yayımlandı J Lipid Res (2018)

A New Paroxetine-Based GRK2 Inhibitor Reduces Internalization of the μ-Opioid Receptor

Yazar: Bouley, Renee A., Weinberg, Zara Y., Waldschmidt, Helen V., Yen, Yu-Chen, Larsen, Scott D., Puthenveedu, Manojkumar A., Tesmer, John J.G.
Yayımlandı Mol Pharmacol (2020)

Structure–Activity Relationship for the 4(3H)-Quinazolinone Antibacterials

Yazar: Bouley, Renee, Ding, Derong, Peng, Zhihong, Bastian, Maria, Lastochkin, Elena, Song, Wei, Suckow, Mark A., Schroeder, Valerie A., Wolter, William R., Mobashery, Shahriar, Chang, Mayland
Yayımlandı J Med Chem (2016)

Structure-Based Design of Selective, Covalent G Protein-Coupled Receptor Kinase 5 Inhibitors

Yazar: Rowlands, Rachel A., Cato, M. Claire, Waldschmidt, Helen V., Bouley, Renee A., Chen, Qiuyan, Avramova, Larisa, Larsen, Scott D., Tesmer, John J. G., White, Andrew D.
Yayımlandı ACS Med Chem Lett (2019)

Structural Determinants Influencing the Potency and Selectivity of Indazole-Paroxetine Hybrid G Protein–Coupled Receptor Kinase 2 Inhibitors

Yazar: Bouley, Renee, Waldschmidt, Helen V., Cato, M. Claire, Cannavo, Alessandro, Song, Jianliang, Cheung, Joseph Y., Yao, Xin-Qiu, Koch, Walter J., Larsen, Scott D., Tesmer, John J. G.
Yayımlandı Mol Pharmacol (2017)

Synergistic, collaterally sensitive β-lactam combinations suppress resistance in MRSA

Yazar: Gonzales, Patrick R., Pesesky, Mitchell W., Bouley, Renee, Ballard, Anna, Biddy, Brent A., Suckow, Mark A., Wolter, William R., Schroeder, Valerie A., Burnham, Carey-Ann D., Mobashery, Shahriar, Chang, Mayland, Dantas, Gautam
Yayımlandı Nat Chem Biol (2015)

The Quinazolinone Allosteric Inhibitor of PBP 2a Synergizes with Piperacillin and Tazobactam against Methicillin-Resistant Staphylococcus aureus

Yazar: Janardhanan, Jeshina, Bouley, Renee, Martínez-Caballero, Siseth, Peng, Zhihong, Batuecas-Mordillo, Mayte, Meisel, Jayda E., Ding, Derong, Schroeder, Valerie A., Wolter, William R., Mahasenan, Kiran V., Hermoso, Juan A., Mobashery, Shahriar, Chang, Mayland
Yayımlandı Antimicrob Agents Chemother (2019)

Discovery of Antibiotic (E)-3-(3-Carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one

Yazar: Bouley, Renee, Kumarasiri, Malika, Peng, Zhihong, Otero, Lisandro H., Song, Wei, Suckow, Mark A., Schroeder, Valerie A., Wolter, William R., Lastochkin, Elena, Antunes, Nuno T., Pi, Hualiang, Vakulenko, Sergei, Hermoso, Juan A., Chang, Mayland, Mobashery, Shahriar
Yayımlandı J Am Chem Soc (2015)