Using antisense technology to develop a novel therapy for α-1 antitrypsin deficient (AATD) liver disease and to model AATD lung disease

Tekijä Guo, Shuling, Booten, Sheri L, Watt, Andrew, Alvarado, Luis, Freier, Susan M, Teckman, Jeffery H, McCaleb, Michael L, Monia, Brett P
Julkaistu 2014

Targeted Delivery of Stk25 Antisense Oligonucleotides to Hepatocytes Protects Mice Against Nonalcoholic Fatty Liver Disease

Tekijä Cansby, Emmelie, Nuñez-Durán, Esther, Magnusson, Elin, Amrutkar, Manoj, Booten, Sheri L., Kulkarni, Nagaraj M., Svensson, L. Thomas, Borén, Jan, Marschall, Hanns-Ulrich, Aghajan, Mariam, Mahlapuu, Margit
Julkaisussa Cell Mol Gastroenterol Hepatol (2018)

Antisense oligonucleotide treatment ameliorates alpha-1 antitrypsin–related liver disease in mice

Tekijä Guo, Shuling, Booten, Sheri L., Aghajan, Mariam, Hung, Gene, Zhao, Chenguang, Blomenkamp, Keith, Gattis, Danielle, Watt, Andrew, Freier, Susan M., Teckman, Jeffery H., McCaleb, Michael L., Monia, Brett P.
Julkaistu 2013

Serine/threonine protein kinase 25 antisense oligonucleotide treatment reverses glucose intolerance, insulin resistance, and nonalcoholic fatty liver disease in mice

Tekijä Nuñez‐Durán, Esther, Aghajan, Mariam, Amrutkar, Manoj, Sütt, Silva, Cansby, Emmelie, Booten, Sheri L., Watt, Andrew, Ståhlman, Marcus, Stefan, Norbert, Häring, Hans‐Ulrich, Staiger, Harald, Borén, Jan, Marschall, Hanns‐Ulrich, Mahlapuu, Margit
Julkaisussa Hepatol Commun (2017)

Inhibition of Protein Tyrosine Phosphatase-1B with Antisense Oligonucleotides Improves Insulin Sensitivity and Increases Adiponectin Concentrations in Monkeys

Tekijä Swarbrick, Michael M., Havel, Peter J., Levin, Arthur A., Bremer, Andrew A., Stanhope, Kimber L., Butler, Madeline, Booten, Sheri L., Graham, James L., McKay, Robert A., Murray, Susan F., Watts, Lynnetta M., Monia, Brett P., Bhanot, Sanjay
Julkaistu 2009

Antisense oligonucleotide treatment ameliorates IFN-γ–induced proteinuria in APOL1-transgenic mice

Tekijä Aghajan, Mariam, Booten, Sheri L., Althage, Magnus, Hart, Christopher E., Ericsson, Anette, Maxvall, Ingela, Ochaba, Joseph, Menschik-Lundin, Angela, Hartleib, Judith, Kuntz, Steven, Gattis, Danielle, Ahlström, Christine, Watt, Andrew T., Engelhardt, Jeffery A., Monia, Brett P., Magnone, Maria Chiara, Guo, Shuling
Julkaisussa JCI Insight (2019)

Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice

Tekijä Prakash, Thazha P., Graham, Mark J., Yu, Jinghua, Carty, Rick, Low, Audrey, Chappell, Alfred, Schmidt, Karsten, Zhao, Chenguang, Aghajan, Mariam, Murray, Heather F., Riney, Stan, Booten, Sheri L., Murray, Susan F., Gaus, Hans, Crosby, Jeff, Lima, Walt F., Guo, Shuling, Monia, Brett P., Swayze, Eric E., Seth, Punit P.
Julkaistu 2014