Protein kinase STK25 aggravates the severity of non-alcoholic fatty pancreas disease in mice

Autor Nuñez-Durán, Esther, Chanclón, Belén, Sütt, Silva, Real, Joana, Marschall, Hanns-Ulrich, Wernstedt Asterholm, Ingrid, Cansby, Emmelie, Mahlapuu, Margit
Vydáno v J Endocrinol (2017)

STE20‐Type Protein Kinase MST4 Controls NAFLD Progression by Regulating Lipid Droplet Dynamics and Metabolic Stress in Hepatocytes

Autor Caputo, Mara, Cansby, Emmelie, Kumari, Sima, Kurhe, Yeshwant, Nair, Syam, Ståhlman, Marcus, Kulkarni, Nagaraj M., Borén, Jan, Marschall, Hanns‐Ulrich, Blüher, Matthias, Mahlapuu, Margit
Vydáno v Hepatol Commun (2021)

Targeted Delivery of Stk25 Antisense Oligonucleotides to Hepatocytes Protects Mice Against Nonalcoholic Fatty Liver Disease

Autor Cansby, Emmelie, Nuñez-Durán, Esther, Magnusson, Elin, Amrutkar, Manoj, Booten, Sheri L., Kulkarni, Nagaraj M., Svensson, L. Thomas, Borén, Jan, Marschall, Hanns-Ulrich, Aghajan, Mariam, Mahlapuu, Margit
Vydáno v Cell Mol Gastroenterol Hepatol (2018)

Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle

Autor Chursa, Urszula, Nuñez-Durán, Esther, Cansby, Emmelie, Amrutkar, Manoj, Sütt, Silva, Ståhlman, Marcus, Olsson, Britt-Marie, Borén, Jan, Johansson, Maria E., Bäckhed, Fredrik, Johansson, Bengt R., Sihlbom, Carina, Mahlapuu, Margit
Vydáno v Diabetologia (2016)

Genetic Disruption of Protein Kinase STK25 Ameliorates Metabolic Defects in a Diet-Induced Type 2 Diabetes Model

Autor Amrutkar, Manoj, Cansby, Emmelie, Chursa, Urszula, Nuñez-Durán, Esther, Chanclón, Belén, Ståhlman, Marcus, Fridén, Vincent, Mannerås-Holm, Louise, Wickman, Anna, Smith, Ulf, Bäckhed, Fredrik, Borén, Jan, Howell, Brian W., Mahlapuu, Margit
Vydáno v Diabetes (2015)

Serine/threonine protein kinase 25 antisense oligonucleotide treatment reverses glucose intolerance, insulin resistance, and nonalcoholic fatty liver disease in mice

Autor Nuñez‐Durán, Esther, Aghajan, Mariam, Amrutkar, Manoj, Sütt, Silva, Cansby, Emmelie, Booten, Sheri L., Watt, Andrew, Ståhlman, Marcus, Stefan, Norbert, Häring, Hans‐Ulrich, Staiger, Harald, Borén, Jan, Marschall, Hanns‐Ulrich, Mahlapuu, Margit
Vydáno v Hepatol Commun (2017)

Depletion of protein kinase STK25 ameliorates renal lipotoxicity and protects against diabetic kidney disease

Autor Cansby, Emmelie, Caputo, Mara, Gao, Lei, Kulkarni, Nagaraj M., Nerstedt, Annika, Ståhlman, Marcus, Borén, Jan, Porosk, Rando, Soomets, Ursel, Pedrelli, Matteo, Parini, Paolo, Marschall, Hanns-Ulrich, Nyström, Jenny, Howell, Brian W., Mahlapuu, Margit
Vydáno v JCI Insight (2020)

Lipid droplet-associated kinase STK25 regulates peroxisomal activity and metabolic stress response in steatotic liver

Autor Nerstedt, Annika, Kurhe, Yeshwant, Cansby, Emmelie, Caputo, Mara, Gao, Lei, Vorontsov, Egor, Ståhlman, Marcus, Nuñez-Durán, Esther, Borén, Jan, Marschall, Hanns-Ulrich, Mashek, Douglas G., Saunders, Darren N., Sihlbom, Carina, Hoy, Andrew J., Mahlapuu, Margit
Vydáno v J Lipid Res (2020)