Evolution of Mammalian Chitinase(-Like) Members of Family 18 Glycosyl Hydrolases

Por Bussink, Anton P., Speijer, Dave, Aerts, Johannes M. F. G., Boot, Rolf G.
Publicado em 2007

Chitotriosidase is the primary active chitinase in the human lung and is modulated by genotype and disease

Por Seibold, Max A., Donnelly, Samantha, Solon, Margaret, Innes, Anh, Woodruff, Prescott G., Boot, Rolf G., Burchard, Esteban González, Fahy, John V.
Publicado em 2008

Investigations on therapeutic glucocerebrosidases through paired detection with fluorescent activity-based probes

Por Kallemeijn, Wouter W., Scheij, Saskia, Hoogendoorn, Sascha, Witte, Martin D., Herrera Moro Chao, Daniela, van Roomen, Cindy P. A. A., Ottenhoff, Roelof, Overkleeft, Herman S., Boot, Rolf G., Aerts, Johannes M. F. G.
Publicado no PLoS One (2017)

Phenotype diversity in type 1 Gaucher disease: discovering the genetic basis of Gaucher disease/hematologic malignancy phenotype by individual genome analysis

Por Lo, Sarah M., Choi, Murim, Liu, Jun, Jain, Dhanpat, Boot, Rolf G., Kallemeijn, Wouter W., Aerts, Johannes M. F. G., Pashankar, Farzana, Kupfer, Gary M., Mane, Shrikant, Lifton, Richard P., Mistry, Pramod K.
Publicado em 2012

Assessment of Partially Deoxygenated Deoxynojirimycin Derivatives as Glucosylceramide Synthase Inhibitors

Por van den Berg, Richard J. B. H. N., Wennekes, Tom, Ghisaidoobe, Amar, Donker-Koopman, Wilma E., Strijland, Anneke, Boot, Rolf G., van der Marel, Gijsbert A., Aerts, Johannes M. F. G., Overkleeft, Herman S.
Publicado em 2011

A Sensitive Gel-based Method Combining Distinct Cyclophellitol-based Probes for the Identification of Acid/Base Residues in Human Retaining β-Glucosidases

Por Kallemeijn, Wouter W., Witte, Martin D., Voorn-Brouwer, Tineke M., Walvoort, Marthe T. C., Li, Kah-Yee, Codée, Jeroen D. C., van der Marel, Gijsbert A., Boot, Rolf G., Overkleeft, Herman S., Aerts, Johannes M. F. G.
Publicado no J Biol Chem (2014)

Detection of Active Mammalian GH31 α-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes

Por Jiang, Jianbing, Kuo, Chi-Lin, Wu, Liang, Franke, Christian, Kallemeijn, Wouter W., Florea, Bogdan I., van Meel, Eline, van der Marel, Gijsbert A., Codée, Jeroen D. C., Boot, Rolf G., Davies, Gideon J., Overkleeft, Herman S., Aerts, Johannes M. F. G.
Publicado no ACS Cent Sci (2016)

Elevation of glycoprotein nonmetastatic melanoma protein B in type 1 Gaucher disease patients and mouse models

Por Kramer, Gertjan, Wegdam, Wouter, Donker‐Koopman, Wilma, Ottenhoff, Roelof, Gaspar, Paulo, Verhoek, Marri, Nelson, Jessica, Gabriel, Tanit, Kallemeijn, Wouter, Boot, Rolf G., Laman, Jon D., Vissers, Johannes P.C., Cox, Timothy, Pavlova, Elena, Moran, Mary Teresa, Aerts, Johannes M., van Eijk, Marco
Publicado no FEBS Open Bio (2016)

Elevated plasma glucosylsphingosine in Gaucher disease: relation to phenotype, storage cell markers, and therapeutic response

Por Dekker, Nick, van Dussen, Laura, Hollak, Carla E. M., Overkleeft, Herman, Scheij, Saskia, Ghauharali, Karen, van Breemen, Mariëlle J., Ferraz, Maria J., Groener, Johanna E. M., Maas, Mario, Wijburg, Frits A., Speijer, Dave, Tylki-Szymanska, Anna, Mistry, Pramod K., Boot, Rolf G., Aerts, Johannes M.
Publicado em 2011

Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice

Por Marques, André R. A., Aten, Jan, Ottenhoff, Roelof, van Roomen, Cindy P. A. A., Herrera Moro, Daniela, Claessen, Nike, Vinueza Veloz, María Fernanda, Zhou, Kuikui, Lin, Zhanmin, Mirzaian, Mina, Boot, Rolf G., De Zeeuw, Chris I., Overkleeft, Herman S., Yildiz, Yildiz, Aerts, Johannes M. F. G.
Publicado no PLoS One (2015)

Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes

Por Herrera Moro Chao, Daniela, Kallemeijn, Wouter W., Marques, Andre R. A., Orre, Marie, Ottenhoff, Roelof, van Roomen, Cindy, Foppen, Ewout, Renner, Maria C., Moeton, Martina, van Eijk, Marco, Boot, Rolf G., Kamphuis, Willem, Hol, Elly M., Aten, Jan, Overkleeft, Hermen S., Kalsbeek, Andries, Aerts, Johannes M. F. G.
Publicado no PLoS One (2015)

Elevated globotriaosylsphingosine is a hallmark of Fabry disease

Por Aerts, Johannes M., Groener, Johanna E., Kuiper, Sijmen, Donker-Koopman, Wilma E., Strijland, Anneke, Ottenhoff, Roelof, van Roomen, Cindy, Mirzaian, Mina, Wijburg, Frits A., Linthorst, Gabor E., Vedder, Anouk C., Rombach, Saskia M., Cox-Brinkman, Josanne, Somerharju, Pentti, Boot, Rolf G., Hollak, Carla E., Brady, Roscoe O., Poorthuis, Ben J.
Publicado em 2008

Biomarkers in the diagnosis of lysosomal storage disorders: proteins, lipids, and inhibodies

Por Aerts, Johannes M. F. G., Kallemeijn, Wouter W., Wegdam, Wouter, Joao Ferraz, Maria, van Breemen, Marielle J., Dekker, Nick, Kramer, Gertjan, Poorthuis, Ben J., Groener, Johanna E. M., Cox-Brinkman, Josanne, Rombach, Saskia M., Hollak, Carla E. M., Linthorst, Gabor E., Witte, Martin D., Gold, Henrik, van der Marel, Gijs A., Overkleeft, Herman S., Boot, Rolf G.
Publicado em 2011

Differential Enzymatic Activity of Common Haplotypic Versions of the Human Acidic Mammalian Chitinase Protein

Por Seibold, Max A., Reese, Tiffany A., Choudhry, Shweta, Salam, Muhammad T., Beckman, Kenny, Eng, Celeste, Atakilit, Amha, Meade, Kelley, Lenoir, Michael, Watson, H. Geoffrey, Thyne, Shannon, Kumar, Rajesh, Weiss, Kevin B., Grammer, Leslie C., Avila, Pedro, Schleimer, Robert P., Fahy, John V., Rodriguez-Santana, Jose, Rodriguez-Cintron, William, Boot, Rolf G., Sheppard, Dean, Gilliland, Frank D., Locksley, Richard M., Burchard, Esteban G.
Publicado em 2009

Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular β-glucosidases

Por Marques, André R. A., Mirzaian, Mina, Akiyama, Hisako, Wisse, Patrick, Ferraz, Maria J., Gaspar, Paulo, Ghauharali-van der Vlugt, Karen, Meijer, Rianne, Giraldo, Pilar, Alfonso, Pilar, Irún, Pilar, Dahl, Maria, Karlsson, Stefan, Pavlova, Elena V., Cox, Timothy M., Scheij, Saskia, Verhoek, Marri, Ottenhoff, Roelof, van Roomen, Cindy P. A. A., Pannu, Navraj S., van Eijk, Marco, Dekker, Nick, Boot, Rolf G., Overkleeft, Herman S., Blommaart, Edward, Hirabayashi, Yoshio, Aerts, Johannes M.
Publicado no J Lipid Res (2016)