Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake

Por Nelson, Jessica Kristine, Cook, Emma Clare Laura, Loregger, Anke, Hoeksema, Marten Anne, Scheij, Saskia, Kovacevic, Igor, Hordijk, Peter Lodewijk, Ovaa, Huib, Zelcer, Noam
Publicado no J Biol Chem (2016)

Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene

Por Cook, Emma C. L., Nelson, Jessica K., Sorrentino, Vincenzo, Koenis, Duco, Moeton, Martina, Scheij, Saskia, Ottenhoff, Roelof, Bleijlevens, Boris, Loregger, Anke, Zelcer, Noam
Publicado no PLoS One (2017)

EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates ABCA1 Abundance and Cholesterol Efflux

Por Nelson, Jessica Kristine, Koenis, Duco Steven, Scheij, Saskia, Cook, Emma Clare Laura, Moeton, Martina, Santos, Ana, Lobaccaro, Jean-Marc Adolphe, Baron, Silvere, Zelcer, Noam
Publicado no Arterioscler Thromb Vasc Biol (2017)

LIM-Only Protein FHL2 Is a Positive Regulator of Liver X Receptors in Smooth Muscle Cells Involved in Lipid Homeostasis

Por Kurakula, Kondababu, Sommer, Daniela, Sokolovic, Milka, Moerland, Perry D., Scheij, Saskia, van Loenen, Pieter B., Koenis, Duco S., Zelcer, Noam, van Tiel, Claudia M., de Vries, Carlie J. M.
Publicado no Mol Cell Biol (2014)

Action myoclonus-renal failure syndrome: diagnostic applications of activity-based probes and lipid analysis

Por Gaspar, Paulo, Kallemeijn, Wouter W., Strijland, Anneke, Scheij, Saskia, Van Eijk, Marco, Aten, Jan, Overkleeft, Herman S., Balreira, Andrea, Zunke, Friederike, Schwake, Michael, Sá Miranda, Clara, Aerts, Johannes M. F. G.
Publicado em 2014

Investigations on therapeutic glucocerebrosidases through paired detection with fluorescent activity-based probes

Por Kallemeijn, Wouter W., Scheij, Saskia, Hoogendoorn, Sascha, Witte, Martin D., Herrera Moro Chao, Daniela, van Roomen, Cindy P. A. A., Ottenhoff, Roelof, Overkleeft, Herman S., Boot, Rolf G., Aerts, Johannes M. F. G.
Publicado no PLoS One (2017)

A PPARγ-Bnip3 Axis Couples Adipose Mitochondrial Fusion-Fission Balance to Systemic Insulin Sensitivity

Por Tol, Marc J., Ottenhoff, Roelof, van Eijk, Marco, Zelcer, Noam, Aten, Jan, Houten, Sander M., Geerts, Dirk, van Roomen, Cindy, Bierlaagh, Marlou C., Scheij, Saskia, Hoeksema, Marten A., Aerts, Johannes M., Bogan, Jonathan S., Dorn, Gerald W., Argmann, Carmen A., Verhoeven, Arthur J.
Publicado no Diabetes (2016)

Elevated plasma glucosylsphingosine in Gaucher disease: relation to phenotype, storage cell markers, and therapeutic response

Por Dekker, Nick, van Dussen, Laura, Hollak, Carla E. M., Overkleeft, Herman, Scheij, Saskia, Ghauharali, Karen, van Breemen, Mariëlle J., Ferraz, Maria J., Groener, Johanna E. M., Maas, Mario, Wijburg, Frits A., Speijer, Dave, Tylki-Szymanska, Anna, Mistry, Pramod K., Boot, Rolf G., Aerts, Johannes M.
Publicado em 2011

Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular β-glucosidases

Por Marques, André R. A., Mirzaian, Mina, Akiyama, Hisako, Wisse, Patrick, Ferraz, Maria J., Gaspar, Paulo, Ghauharali-van der Vlugt, Karen, Meijer, Rianne, Giraldo, Pilar, Alfonso, Pilar, Irún, Pilar, Dahl, Maria, Karlsson, Stefan, Pavlova, Elena V., Cox, Timothy M., Scheij, Saskia, Verhoek, Marri, Ottenhoff, Roelof, van Roomen, Cindy P. A. A., Pannu, Navraj S., van Eijk, Marco, Dekker, Nick, Boot, Rolf G., Overkleeft, Herman S., Blommaart, Edward, Hirabayashi, Yoshio, Aerts, Johannes M.
Publicado no J Lipid Res (2016)