Nuclear Receptor Nur77 Controls Cardiac Fibrosis through Distinct Actions on Fibroblasts and Cardiomyocytes

por Medzikovic, Lejla, Heese, Hylja, van Loenen, Pieter B., van Roomen, Cindy P. A. A., Hooijkaas, Ingeborg B., Christoffels, Vincent M., Creemers, Esther E., de Vries, Carlie J. M., de Waard, Vivian
Publicado en Int J Mol Sci (2021)

Investigations on therapeutic glucocerebrosidases through paired detection with fluorescent activity-based probes

por Kallemeijn, Wouter W., Scheij, Saskia, Hoogendoorn, Sascha, Witte, Martin D., Herrera Moro Chao, Daniela, van Roomen, Cindy P. A. A., Ottenhoff, Roelof, Overkleeft, Herman S., Boot, Rolf G., Aerts, Johannes M. F. G.
Publicado en PLoS One (2017)

Gpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C Disease

por Marques, André R. A., Gabriel, Tanit L., Aten, Jan, van Roomen, Cindy P. A. A., Ottenhoff, Roelof, Claessen, Nike, Alfonso, Pilar, Irún, Pilar, Giraldo, Pilar, Aerts, Johannes M. F. G., van Eijk, Marco
Publicado en PLoS One (2016)

Correction of Liver Steatosis by a Hydrophobic Iminosugar Modulating Glycosphingolipids Metabolism

por Lombardo, Elisa, van Roomen, Cindy P. A. A., van Puijvelde, Gijs H., Ottenhoff, Roelof, van Eijk, Marco, Aten, Jan, Kuiper, Johan, Overkleeft, Herman S., Groen, Albert K., Verhoeven, Arthur J., Aerts, Johannes M. F. G., Bietrix, Florence
Publicado 2012

Reducing Glycosphingolipid Content in Adipose Tissue of Obese Mice Restores Insulin Sensitivity, Adipogenesis and Reduces Inflammation

por van Eijk, Marco, Aten, Jan, Bijl, Nora, Ottenhoff, Roelof, van Roomen, Cindy P. A. A., Dubbelhuis, Peter F., Seeman, Ingar, Ghauharali-van der Vlugt, Karen, Overkleeft, Hermen S., Arbeeny, Cynthia, Groen, Albert K., Aerts, Johannes M. F. G.
Publicado 2009

Peritoneal macrophages have an impaired immune response in obesity which can be reversed by subsequent weight loss

por Willemsen, Lisa, Neele, Annette E, van der Velden, Saskia, Prange, Koen H M, den Toom, Myrthe, van Roomen, Cindy P A A, Reiche, Myrthe E, Griffith, Guillermo R, Gijbels, Marion J J, Lutgens, Esther, de Winther, Menno P J
Publicado en BMJ Open Diabetes Res Care (2019)

Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice

por Marques, André R. A., Aten, Jan, Ottenhoff, Roelof, van Roomen, Cindy P. A. A., Herrera Moro, Daniela, Claessen, Nike, Vinueza Veloz, María Fernanda, Zhou, Kuikui, Lin, Zhanmin, Mirzaian, Mina, Boot, Rolf G., De Zeeuw, Chris I., Overkleeft, Herman S., Yildiz, Yildiz, Aerts, Johannes M. F. G.
Publicado en PLoS One (2015)

Stabilization of Glucocerebrosidase by Active Site Occupancy

por Ben Bdira, Fredj, Kallemeijn, Wouter W., Oussoren, Saskia V., Scheij, Saskia, Bleijlevens, Boris, Florea, Bogdan I., van Roomen, Cindy P. A. A., Ottenhoff, Roelof, van Kooten, Marielle J. F. M., Walvoort, Marthe T. C., Witte, Martin D., Boot, Rolf G., Ubbink, Marcellus, Overkleeft, Herman S., Aerts, Johannes M. F. G.
Publicado en ACS Chem Biol (2017)

Nanoparticle-Aided Characterization of Arterial Endothelial Architecture during Atherosclerosis Progression and Metabolic Therapy

por Beldman, Thijs J., Malinova, Tsveta S., Desclos, Emilie, Grootemaat, Anita E., Misiak, Aresh L. S., van der Velden, Saskia, van Roomen, Cindy P. A. A., Beckers, Linda, van Veen, Henk A., Krawczyk, Przemyslaw M., Hoebe, Ron A., Sluimer, Judith C., Neele, Annette E., de Winther, Menno P. J., van der Wel, Nicole N., Lutgens, Esther, Mulder, Willem J. M., Huveneers, Stephan, Kluza, Ewelina
Publicado en ACS Nano (2019)

Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular β-glucosidases

por Marques, André R. A., Mirzaian, Mina, Akiyama, Hisako, Wisse, Patrick, Ferraz, Maria J., Gaspar, Paulo, Ghauharali-van der Vlugt, Karen, Meijer, Rianne, Giraldo, Pilar, Alfonso, Pilar, Irún, Pilar, Dahl, Maria, Karlsson, Stefan, Pavlova, Elena V., Cox, Timothy M., Scheij, Saskia, Verhoek, Marri, Ottenhoff, Roelof, van Roomen, Cindy P. A. A., Pannu, Navraj S., van Eijk, Marco, Dekker, Nick, Boot, Rolf G., Overkleeft, Herman S., Blommaart, Edward, Hirabayashi, Yoshio, Aerts, Johannes M.
Publicado en J Lipid Res (2016)

High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages

por Hoepel, Willianne, Chen, Hung-Jen, Geyer, Chiara E., Allahverdiyeva, Sona, Manz, Xue D., de Taeye, Steven W., Aman, Jurjan, Mes, Lynn, Steenhuis, Maurice, Griffith, Guillermo R., Bonta, Peter I., Brouwer, Philip J.M., Caniels, Tom G., van der Straten, Karlijn, Golebski, Korneliusz, Jonkers, René E., Larsen, Mads D., Linty, Federica, Nouta, Jan, van Roomen, Cindy P.A.A., van Baarle, Frank E.H.P., van Drunen, Cornelis M., Wolbink, Gertjan, Vlaar, Alexander P.J., de Bree, Godelieve J., Sanders, Rogier W., Willemsen, Lisa, Neele, Annette E., van de Beek, Diederik, Rispens, Theo, Wuhrer, Manfred, Bogaard, Harm Jan, van Gils, Marit J., Vidarsson, Gestur, de Winther, Menno, den Dunnen, Jeroen
Publicado en Sci Transl Med (2021)