Sensitivity to temozolomide in brain tumor initiating cells

Por Blough, Michael D., Westgate, Morgan R., Beauchamp, Desiree, Kelly, John J., Stechishin, Owen, Ramirez, Andrea L., Weiss, Samuel, Cairncross, J. Gregory
Publicado em 2010

On-target JAK2/STAT3 inhibition slows disease progression in orthotopic xenografts of human glioblastoma brain tumor stem cells

Por Stechishin, Owen D., Luchman, H. Artee, Ruan, Yibing, Blough, Michael D., Nguyen, Stephanie A., Kelly, John J., Cairncross, J. Gregory, Weiss, Samuel
Publicado em 2013

Comparative genomic and genetic analysis of glioblastoma-derived brain tumor-initiating cells and their parent tumors

Por Davis, Brad, Shen, Yaoqing, Poon, Candice C., Luchman, H. Artee, Stechishin, Owen D., Pontifex, Carly S., Wu, Wei, Kelly, John J., Blough, Michael D.
Publicado no Neuro Oncol (2016)

Hyperpolarized (13)C MR imaging detects no lactate production in mutant IDH1 gliomas: Implications for diagnosis and response monitoring

Por Chaumeil, Myriam M., Radoul, Marina, Najac, Chloé, Eriksson, Pia, Viswanath, Pavithra, Blough, Michael D., Chesnelong, Charles, Luchman, H. Artee, Cairncross, J. Gregory, Ronen, Sabrina M.
Publicado no Neuroimage Clin (2016)

An in vivo patient-derived model of endogenous IDH1-mutant glioma

Por Luchman, H. Artee, Stechishin, Owen D., Dang, N. Ha, Blough, Michael D., Chesnelong, Charles, Kelly, John J., Nguyen, Stephanie A., Chan, Jennifer A., Weljie, Aalim M., Cairncross, J. Gregory, Weiss, Samuel
Publicado em 2012

Lactate dehydrogenase A silencing in IDH mutant gliomas

Por Chesnelong, Charles, Chaumeil, Myriam M., Blough, Michael D., Al-Najjar, Mohammad, Stechishin, Owen D., Chan, Jennifer A., Pieper, Russell O., Ronen, Sabrina M., Weiss, Samuel, Luchman, H. Artee, Cairncross, J. Gregory
Publicado em 2014

A novel C19MC amplified cell line links Lin28/let-7 to mTOR signaling in embryonal tumor with multilayered rosettes

Por Spence, Tara, Perotti, Christian, Sin-Chan, Patrick, Picard, Daniel, Wu, Wei, Singh, Anjali, Anderson, Colleen, Blough, Michael D., Cairncross, J. Gregory, Lafay-Cousin, Lucie, Strother, Douglas, Hawkins, Cynthia, Narendran, Aru, Huang, Annie, Chan, Jennifer A.
Publicado em 2014

Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors

Por Ahmad, Shiekh Tanveer, Rogers, Alexandra D., Chen, Myra J., Dixit, Rajiv, Adnani, Lata, Frankiw, Luke S., Lawn, Samuel O., Blough, Michael D., Alshehri, Mana, Wu, Wei, Marra, Marco A., Robbins, Stephen M., Cairncross, J. Gregory, Schuurmans, Carol, Chan, Jennifer A.
Publicado no Nat Commun (2019)

Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity

Por Chittaranjan, Suganthi, Chan, Susanna, Yang, Cindy, Yang, Kevin C., Chen, Vincent, Moradian, Annie, Firme, Marlo, Song, Jungeun, Go, Nancy E., Blough, Michael D., Chan, Jennifer A., Cairncross, J. Gregory, Gorski, Sharon M., Morin, Gregg B., Yip, Stephen, Marra, Marco A.
Publicado em 2014

Oligodendroglioma cell lines containing t(1;19)(q10;p10)

Por Kelly, John J. P., Blough, Michael D., Stechishin, Owen D. M., Chan, Jennifer A. W., Beauchamp, Desiree, Perizzolo, Marco, Demetrick, Doug J., Steele, Lisa, Auer, Roland N., Hader, Walter J., Westgate, Morgan, Parney, Ian F., Jenkins, Robert, Cairncross, J. Gregory, Weiss, Samuel
Publicado em 2010

Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells

Por Grinshtein, Natalie, Rioseco, Constanza C., Marcellus, Richard, Uehling, David, Aman, Ahmed, Lun, Xueqing, Muto, Osamu, Podmore, Lauren, Lever, Jake, Shen, Yaoqing, Blough, Michael D., Cairncross, Greg J., Robbins, Stephen M., Jones, Steven J., Marra, Marco A., Al-Awar, Rima, Senger, Donna L., Kaplan, David R.
Publicado no Oncotarget (2016)

ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts

Por Yuan, Alice L., Ricks, Christian B., Bohm, Alexandra K., Lun, Xueqing, Maxwell, Lori, Safdar, Shahana, Bukhari, Shazreh, Gerber, Amanda, Sayeed, Wajid, Bering, Elizabeth. A., Pedersen, Haley, Chan, Jennifer A., Shen, Yaoqing, Marra, Marco, Kaplan, David R., Mason, Warren, Goodman, Lindsey D., Ezhilarasan, Ravesanker, Kaufmann, Ascher B., Cabral, Matthew, Robbins, Steve M., Senger, Donna L., Cahill, Daniel P., Sulman, Erik P., Cairncross, J. Gregory, Blough, Michael D.
Publicado no PLoS One (2018)

Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and adaptation to growth environments

Por Shen, Yaoqing, Grisdale, Cameron J., Islam, Sumaiya A., Bose, Pinaki, Lever, Jake, Zhao, Eric Y., Grinshtein, Natalie, Ma, Yussanne, Mungall, Andrew J., Moore, Richard A., Lun, Xueqing, Senger, Donna L., Robbins, Stephen M., Wang, Alice Yijun, MacIsaac, Julia L., Kobor, Michael S., Luchman, H. Artee, Weiss, Samuel, Chan, Jennifer A., Blough, Michael D., Kaplan, David R., Cairncross, J. Gregory, Marra, Marco A., Jones, Steven J. M.
Publicado no Proc Natl Acad Sci U S A (2019)

Concurrent CIC mutations, IDH mutations and 1p/19q loss distinguish oligodendrogliomas from other cancers

Por Yip, Stephen, Butterfield, Yaron S, Morozova, Olena, Chittaranjan, Suganthi, Blough, Michael D, An, Jianghong, Birol, Inanc, Chesnelong, Charles, Chiu, Readman, Chuah, Eric, Corbett, Richard, Docking, Rod, Firme, Marlo, Hirst, Martin, Jackman, Shaun, Karsan, Aly, Li, Haiyan, Louis, David N, Maslova, Alexandra, Moore, Richard, Moradian, Annie, Mungall, Karen L, Perizzolo, Marco, Qian, Jenny, Roldan, Gloria, Smith, Eric E, Tamura-Wells, Jessica, Thiessen, Nina, Varhol, Richard, Weiss, Samuel, Wu, Wei, Young, Sean, Zhao, Yongjun, Mungall, Andrew J, Jones, Steven JM, Morin, Gregg B, Chan, Jennifer A, Cairncross, J Gregory, Marra, Marco A
Publicado em 2011