A novel C19MC amplified cell line links Lin28/let-7 to mTOR signaling in embryonal tumor with multilayered rosettes

BACKGROUND: Embryonal tumor with multilayered rosettes (ETMR) is an aggressive central nervous system primitive neuroectodermal tumor (CNS-PNET) variant. ETMRs have distinctive histology, amplification of the chromosome 19 microRNA cluster (C19MC) at chr19q13.41-42, expression of the RNA binding pro...

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Detalhes bibliográficos
Main Authors: Spence, Tara, Perotti, Christian, Sin-Chan, Patrick, Picard, Daniel, Wu, Wei, Singh, Anjali, Anderson, Colleen, Blough, Michael D., Cairncross, J. Gregory, Lafay-Cousin, Lucie, Strother, Douglas, Hawkins, Cynthia, Narendran, Aru, Huang, Annie, Chan, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870842/
https://ncbi.nlm.nih.gov/pubmed/24311633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not162
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