Lund Human Mesencephalic (LUHMES) Neuronal Cell Line Supports Herpes Simplex Virus 1 Latency In Vitro

by Edwards, Terri G., Bloom, David C.
Published in J Virol (2019)

Herpes Simplex Viruses Whose Replication Can Be Deliberately Controlled as Candidate Vaccines

by Voellmy, Richard, Bloom, David C, Vilaboa, Nuria
Published in Vaccines (Basel) (2020)

The ATM and Rad3-Related (ATR) Protein Kinase Pathway Is Activated by Herpes Simplex Virus 1 and Required for Efficient Viral Replication

by Edwards, Terri G., Bloom, David C., Fisher, Chris
Published in J Virol (2018)

The Polycomb Group Protein Bmi1 Binds to the Herpes Simplex Virus 1 Latent Genome and Maintains Repressive Histone Marks during Latency

by Kwiatkowski, Dacia L., Thompson, Hilary W., Bloom, David C.
Published 2009

Epigenetic regulation of latent HSV-1 gene expression

by Bloom, David C., Giordani, Nicole V., Kwiatkowski, Dacia L.
Published 2010

Herpes Simplex Virus 1 Strains 17syn(+) and KOS(M) Differ Greatly in Their Ability To Reactivate from Human Neurons In Vitro

by Grams, Tristan R., Edwards, Terri G., Bloom, David C.
Published in J Virol (2020)

A Chromatin Insulator-Like Element in the Herpes Simplex Virus Type 1 Latency-Associated Transcript Region Binds CCCTC-Binding Factor and Displays Enhancer-Blocking and Silencing A...

by Amelio, Antonio L., McAnany, Peterjon K., Bloom, David C.
Published 2006

Immunization by Replication-Competent Controlled Herpesvirus Vectors

by Bloom, David C., Tran, Robert K., Feller, Joyce, Voellmy, Richard
Published in J Virol (2018)

Inhibition of H3K27me3-Specific Histone Demethylases JMJD3 and UTX Blocks Reactivation of Herpes Simplex Virus 1 in Trigeminal Ganglion Neurons

by Messer, Harald G. P., Jacobs, Derek, Dhummakupt, Adit, Bloom, David C.
Published in J Virol (2014)

Specific Histone Tail Modification and Not DNA Methylation Is a Determinant of Herpes Simplex Virus Type 1 Latent Gene Expression

by Kubat, Nicole J., Tran, Robert K., McAnany, Peterjon, Bloom, David C.
Published 2004

The Herpes Simplex Virus Type 1 Latency-Associated Transcript (LAT) Enhancer/rcr Is Hyperacetylated during Latency Independently of LAT Transcription

by Kubat, Nicole J., Amelio, Antonio L., Giordani, Nicole V., Bloom, David C.
Published 2004

Replication-Competent Controlled Herpes Simplex Virus

by Bloom, David C., Feller, Joyce, McAnany, Peterjon, Vilaboa, Nuria, Voellmy, Richard
Published in J Virol (2015)

Altering the Expression Kinetics of VP5 Results in Altered Virulence and Pathogenesis of Herpes Simplex Virus Type 1 in Mice

by Tran, Robert K., Lieu, Pauline T., Aguilar, Santiago, Wagner, Edward K., Bloom, David C.
Published 2002

Herpes Simplex Virus 1 MicroRNA miR-H8 Is Dispensable for Latency and Reactivation In Vivo

by Barrozo, Enrico R., Nakayama, Sanae, Singh, Pankaj, Neumann, Donna M., Bloom, David C.
Published in J Virol (2021)

In Vivo Changes in the Patterns of Chromatin Structure Associated with the Latent Herpes Simplex Virus Type 1 Genome in Mouse Trigeminal Ganglia Can Be Detected at Early Times afte...

by Neumann, Donna M., Bhattacharjee, Partha S., Giordani, Nicole V., Bloom, David C., Hill, James M.
Published 2007

Reduction in Severity of a Herpes Simplex Virus Type 1 Murine Infection by Treatment with a Ribozyme Targeting the U(L)20 Gene RNA

by Liu, Jia, Lewin, Alfred S., Tuli, Sonal S., Ghivizzani, Steven C., Schultz, Gregory S., Bloom, David C.
Published 2008

FRAGILE X MENTAL RETARDATION PROTEIN REPLACEMENT RESTORES HIPPOCAMPAL SYNAPTIC FUNCTION IN A MOUSE MODEL OF FRAGILE X SYNDROME

by Zeier, Zane, Kumar, Ashok, Bodhinathan, Karthik, Feller, Joyce A., Foster, Thomas C., Bloom, David C.
Published 2009

Mutational Inactivation of Herpes Simplex Virus 1 MicroRNAs Identifies Viral mRNA Targets and Reveals Phenotypic Effects in Culture

by Flores, Omar, Nakayama, Sanae, Whisnant, Adam W., Javanbakht, Hassan, Cullen, Bryan R., Bloom, David C.
Published 2013

Deacetylation of the Herpes Simplex Virus Type 1 Latency-Associated Transcript (LAT) Enhancer and a Decrease in LAT Abundance Precede an Increase in ICP0 Transcriptional Permissive...

by Amelio, Antonio L., Giordani, Nicole V., Kubat, Nicole J., O'Neil, Jerome E., Bloom, David C.
Published 2006

Reliable Detection of Herpes Simplex Virus Sequence Variation by High-Throughput Resequencing

by Morse, Alison M., Calabro, Kaitlyn R., Fear, Justin M., Bloom, David C., McIntyre, Lauren M.
Published in Viruses (2017)