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In Vivo Changes in the Patterns of Chromatin Structure Associated with the Latent Herpes Simplex Virus Type 1 Genome in Mouse Trigeminal Ganglia Can Be Detected at Early Times after Butyrate Treatment

During herpes simplex virus type 1 (HSV-1) latency in mouse dorsal root ganglia (DRG), chromatin associated with the latency-associated transcript (LAT) region of the viral genome is hyperacetylated at lysines 9 and 14 of histone 3 [H3(K9, K14)], while lytic genes are hypoacetylated. Explanted DRG e...

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Detalhes bibliográficos
Main Authors: Neumann, Donna M., Bhattacharjee, Partha S., Giordani, Nicole V., Bloom, David C., Hill, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169074/
https://ncbi.nlm.nih.gov/pubmed/17881451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01569-07
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