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FRAGILE X MENTAL RETARDATION PROTEIN REPLACEMENT RESTORES HIPPOCAMPAL SYNAPTIC FUNCTION IN A MOUSE MODEL OF FRAGILE X SYNDROME
Fragile X Syndrome (FXS) is caused by a mutation that silences the Fragile X Mental Retardation gene (FMR1) which encodes the Fragile X Mental Retardation Protein (FMRP). To determine if FMRP replacement can rescue phenotypic deficits in an fmr1 knockout (KO) mouse model of FXS, we constructed an Ad...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2741536/ https://ncbi.nlm.nih.gov/pubmed/19571888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2009.83 |
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