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Temporal Requirements of the Fragile X Mental Retardation Protein in the Regulation of Synaptic Structure

Fragile X Syndrome (FraX), caused by the loss of function of one gene (FMR1), is the most common inherited form of both mental retardation and autism spectrum disorders. The FMR1 product (FMRP) is an mRNA-binding translation regulator that mediates activity-dependent control of synaptic structure an...

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Bibliografske podrobnosti
Main Authors: Gatto, Cheryl L., Broadie, Kendal
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753511/
https://ncbi.nlm.nih.gov/pubmed/18579676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.022244
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