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Temporal Requirements of the Fragile X Mental Retardation Protein in the Regulation of Synaptic Structure
Fragile X Syndrome (FraX), caused by the loss of function of one gene (FMR1), is the most common inherited form of both mental retardation and autism spectrum disorders. The FMR1 product (FMRP) is an mRNA-binding translation regulator that mediates activity-dependent control of synaptic structure an...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2753511/ https://ncbi.nlm.nih.gov/pubmed/18579676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.022244 |
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