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Fragile X Mental Retardation Protein is Required for Programmed Cell Death and Clearance of Developmentally-Transient Peptidergic Neurons

Fragile X syndrome (FXS), caused by loss of fragile X mental retardation 1 (FMR1) gene function, is the most common heritable cause of intellectual disability and autism spectrum disorders. The FMR1 product (FMRP) is an RNA-binding protein best established to function in activity-dependent modulatio...

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Detalhes bibliográficos
Main Authors: Gatto, Cheryl L., Broadie, Kendal
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143227/
https://ncbi.nlm.nih.gov/pubmed/21596027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.05.001
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