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Drosophila Fragile X Mental Retardation Protein Developmentally Regulates Activity-Dependent Axon Pruning

Fragile X Syndrome (FraX) is a broad-spectrum neurological disorder with symptoms ranging from hyperexcitability to mental retardation and autism. Loss of the fragile X mental retardation 1 (fmr1) gene product, the mRNA-binding translational regulator FMRP, causes structural over-elaboration of dend...

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Autors principals: Tessier, Charles R., Broadie, Kendal
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988902/
https://ncbi.nlm.nih.gov/pubmed/18321984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.015867
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