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Drosophila Fragile X Mental Retardation Protein Developmentally Regulates Activity-Dependent Axon Pruning
Fragile X Syndrome (FraX) is a broad-spectrum neurological disorder with symptoms ranging from hyperexcitability to mental retardation and autism. Loss of the fragile X mental retardation 1 (fmr1) gene product, the mRNA-binding translational regulator FMRP, causes structural over-elaboration of dend...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3988902/ https://ncbi.nlm.nih.gov/pubmed/18321984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.015867 |
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