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Altered synaptic plasticity in a mouse model of fragile X mental retardation

Fragile X syndrome, the most common inherited form of human mental retardation, is caused by mutations of the Fmr1 gene that encodes the fragile X mental retardation protein (FMRP). Biochemical evidence indicates that FMRP binds a subset of mRNAs and acts as a regulator of translation. However, the...

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Detalhes bibliográficos
Main Authors: Huber, Kimberly M., Gallagher, Sean M., Warren, Stephen T., Bear, Mark F.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124340/
https://ncbi.nlm.nih.gov/pubmed/12032354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122205699
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