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Fragile X mental retardation protein and synaptic plasticity

Loss of the translational repressor FMRP causes Fragile X syndrome. In healthy neurons, FMRP modulates the local translation of numerous synaptic proteins. Synthesis of these proteins is required for the maintenance and regulation of long-lasting changes in synaptic strength. In this role as a trans...

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Detalhes bibliográficos
Main Authors: Sidorov, Michael S, Auerbach, Benjamin D, Bear, Mark F
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636002/
https://ncbi.nlm.nih.gov/pubmed/23566911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-15
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