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Fragile X mental retardation protein and synaptic plasticity
Loss of the translational repressor FMRP causes Fragile X syndrome. In healthy neurons, FMRP modulates the local translation of numerous synaptic proteins. Synthesis of these proteins is required for the maintenance and regulation of long-lasting changes in synaptic strength. In this role as a trans...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3636002/ https://ncbi.nlm.nih.gov/pubmed/23566911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-15 |
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