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Fragile X mental retardation protein regulates heterosynaptic plasticity in the hippocampus

Silencing of a single gene, FMR1, is linked to a highly prevalent form of mental retardation, characterized by social and cognitive impairments, known as fragile X syndrome (FXS). The FMR1 gene encodes fragile X mental retardation protein (FMRP), which negatively regulates translation. Knockout of F...

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Detalhes bibliográficos
Main Authors: Connor, Steven A., Hoeffer, Charles A., Klann, Eric, Nguyen, Peter V.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072772/
https://ncbi.nlm.nih.gov/pubmed/21430043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.2043811
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