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Fragile X mental retardation protein regulates heterosynaptic plasticity in the hippocampus

Silencing of a single gene, FMR1, is linked to a highly prevalent form of mental retardation, characterized by social and cognitive impairments, known as fragile X syndrome (FXS). The FMR1 gene encodes fragile X mental retardation protein (FMRP), which negatively regulates translation. Knockout of F...

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書誌詳細
主要な著者: Connor, Steven A., Hoeffer, Charles A., Klann, Eric, Nguyen, Peter V.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2011
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072772/
https://ncbi.nlm.nih.gov/pubmed/21430043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.2043811
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