geneAttribution: trait agnostic identification of candidate genes associated with noncoding variation

Por Wuster, Arthur, Chang, Diana, Behrens, Timothy W, Bhangale, Tushar R
Publicado no Bioinformatics (2017)

Using Gene Expression to Improve the Power of Genome-Wide Association Analysis

Por Ho, Yen-Yi, Baechler, Emily C., Ortmann, Ward, Behrens, Timothy W., Graham, Robert R., Bhangale, Tushar R., Pan, Wei
Publicado em 2014

Identifying and mitigating batch effects in whole genome sequencing data

Por Tom, Jennifer A., Reeder, Jens, Forrest, William F., Graham, Robert R., Hunkapiller, Julie, Behrens, Timothy W., Bhangale, Tushar R.
Publicado no BMC Bioinformatics (2017)

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus

Por Cunninghame Graham, Deborah S., Morris, David L., Bhangale, Tushar R., Criswell, Lindsey A., Syvänen, Ann-Christine, Rönnblom, Lars, Behrens, Timothy W., Graham, Robert R., Vyse, Timothy J.
Publicado em 2011

A meta-analysis of genome-wide association studies identifies 17 new Parkinson’s disease risk loci

Por Chang, Diana, Nalls, Mike A, Hallgrímsdóttir, Ingileif B, Hunkapiller, Julie, van der Brug, Marcel, Cai, Fang, Kerchner, Geoffrey A, Ayalon, Gai, Bingol, Baris, Sheng, Morgan, Hinds, David, Behrens, Timothy W, Singleton, Andrew B, Bhangale, Tushar R, Graham, Robert R
Publicado no Nat Genet (2017)

Evaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection

Por Randolph, Adrienne G., Yip, Wai-Ki, Allen, Emma Kaitlynn, Rosenberger, Carrie M., Agan, Anna A., Ash, Stephanie A., Zhang, Yu, Bhangale, Tushar R., Finkelstein, David, Cvijanovich, Natalie Z., Mourani, Peter M., Hall, Mark W., Su, Helen C., Thomas, Paul G.
Publicado no J Infect Dis (2017)

Previously reported placebo-response-associated variants do not predict patient outcomes in inflammatory disease Phase III trial placebo arms

Por Haug-Baltzell, Asher, Bhangale, Tushar R., Chang, Diana, Dressen, Amy, Yaspan, Brian L., Ortmann, Ward, Brauer, Matthew J., Hunkapiller, Julie, Reeder, Jens, Mukhyala, Kiran, Cuenco, Karen T., Tom, Jennifer A., Cowgill, Amy, Vogel, Jan, Forrest, William F., Behrens, Timothy W., Graham, Robert R., Wuster, Arthur
Publicado no Genes Immun (2018)

A common variant of IL-6R is associated with elevated IL-6 pathway activity in Alzheimer’s disease brains

Por Haddick, Patrick C.G., Larson, Jessica L., Rathore, Nisha, Bhangale, Tushar R., Phung, Qui T., Srinivasan, Karpagam, Hansen, David V., Lill, Jennie R., Pericak-Vance, Margaret A., Haines, Jonathan, Farrer, Lindsay A., Kauwe, John S., Schellenberg, Gerard D., Cruchaga, Carlos, Goate, Alison M., Behrens, Timothy W., Watts, Ryan J., Graham, Robert R., Kaminker, Joshua S., van der Brug, Marcel
Publicado no J Alzheimers Dis (2017)

Analysis of protein-altering variants in telomerase genes and their association with MUC5B common variant status in patients with idiopathic pulmonary fibrosis: a candidate gene se...

Por Dressen, Amy, Abbas, Alexander R., Cabanski, Christopher, Reeder, Janina, Ramalingam, Thirumalai R., Neighbors, Margaret, Bhangale, Tushar R., Brauer, Matthew J., Hunkapiller, Julie, Reeder, Jens, Mukhyala, Kiran, Cuenco, Karen, Tom, Jennifer, Cowgill, Amy, Vogel, Jan, Forrest, William F., Collard, Harold R., Wolters, Paul J., Kropski, Jonathan A., Lancaster, Lisa H., Blackwell, Timothy S., Arron, Joseph R., Yaspan, Brian L.
Publicado no Lancet Respir Med (2018)

Heritability and Genome-wide Association Study To Assess Genetic Differences Between Advanced Age-Related Macular Degeneration Subtypes

Por Sobrin, Lucia, Ripke, Stephan, Yu, Yi, Fagerness, Jesen, Bhangale, Tushar R., Tan, Perciliz L., Souied, Eric H., Buitendijk, Gabriëlle H.S., Merriam, Joanna E., Richardson, Andrea J., Raychaudhuri, Soumya, Reynolds, Robyn, Chin, Kimberly A., Lee, Aaron Y., Leveziel, Nicolas, Zack, Donald J., Campochiaro, Peter, Smith, R. Theodore, Barile, Gaetano R., Hogg, Ruth E., Chakravarthy, Usha, Behrens, Timothy W., Uitterlinden, André G., van Duijn, Cornelia M., Vingerling, Johannes R., Brantley, Milam A., Baird, Paul N., Klaver, Caroline C.W., Allikmets, Rando, Katsanis, Nicholas, Graham, Robert R., Ioannidis, John P.A., Daly, Mark J., Seddon, Johanna M.
Publicado em 2012

Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration

Por Yu, Yi, Bhangale, Tushar R., Fagerness, Jesen, Ripke, Stephan, Thorleifsson, Gudmar, Tan, Perciliz L., Souied, Eric H., Richardson, Andrea J., Merriam, Joanna E., Buitendijk, Gabriëlle H.S., Reynolds, Robyn, Raychaudhuri, Soumya, Chin, Kimberly A., Sobrin, Lucia, Evangelou, Evangelos, Lee, Phil H., Lee, Aaron Y., Leveziel, Nicolas, Zack, Donald J., Campochiaro, Betsy, Campochiaro, Peter, Smith, R. Theodore, Barile, Gaetano R., Guymer, Robyn H., Hogg, Ruth, Chakravarthy, Usha, Robman, Luba D., Gustafsson, Omar, Sigurdsson, Haraldur, Ortmann, Ward, Behrens, Timothy W., Stefansson, Kari, Uitterlinden, André G., van Duijn, Cornelia M., Vingerling, Johannes R., Klaver, Caroline C.W., Allikmets, Rando, Brantley, Milam A., Baird, Paul N., Katsanis, Nicholas, Thorsteinsdottir, Unnur, Ioannidis, John P.A., Daly, Mark J., Graham, Robert R., Seddon, Johanna M.
Publicado em 2011

TYK2 Protein-Coding Variants Protect against Rheumatoid Arthritis and Autoimmunity, with No Evidence of Major Pleiotropic Effects on Non-Autoimmune Complex Traits

Por Diogo, Dorothée, Bastarache, Lisa, Liao, Katherine P., Graham, Robert R., Fulton, Robert S., Greenberg, Jeffrey D., Eyre, Steve, Bowes, John, Cui, Jing, Lee, Annette, Pappas, Dimitrios A., Kremer, Joel M., Barton, Anne, Coenen, Marieke J. H., Franke, Barbara, Kiemeney, Lambertus A., Mariette, Xavier, Richard-Miceli, Corrine, Canhão, Helena, Fonseca, João E., de Vries, Niek, Tak, Paul P., Crusius, J. Bart A., Nurmohamed, Michael T., Kurreeman, Fina, Mikuls, Ted R., Okada, Yukinori, Stahl, Eli A., Larson, David E., Deluca, Tracie L., O'Laughlin, Michelle, Fronick, Catrina C., Fulton, Lucinda L., Kosoy, Roman, Ransom, Michael, Bhangale, Tushar R., Ortmann, Ward, Cagan, Andrew, Gainer, Vivian, Karlson, Elizabeth W., Kohane, Isaac, Murphy, Shawn N., Martin, Javier, Zhernakova, Alexandra, Klareskog, Lars, Padyukov, Leonid, Worthington, Jane, Mardis, Elaine R., Seldin, Michael F., Gregersen, Peter K., Behrens, Timothy, Raychaudhuri, Soumya, Denny, Joshua C., Plenge, Robert M.
Publicado no PLoS One (2015)

Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci

Por Asselbergs, Folkert W., Guo, Yiran, van Iperen, Erik P.A., Sivapalaratnam, Suthesh, Tragante, Vinicius, Lanktree, Matthew B., Lange, Leslie A., Almoguera, Berta, Appelman, Yolande E., Barnard, John, Baumert, Jens, Beitelshees, Amber L., Bhangale, Tushar R., Chen, Yii-Der Ida, Gaunt, Tom R., Gong, Yan, Hopewell, Jemma C., Johnson, Toby, Kleber, Marcus E., Langaee, Taimour Y., Li, Mingyao, Li, Yun R., Liu, Kiang, McDonough, Caitrin W., Meijs, Matthijs F.L., Middelberg, Rita P.S., Musunuru, Kiran, Nelson, Christopher P., O’Connell, Jeffery R., Padmanabhan, Sandosh, Pankow, James S., Pankratz, Nathan, Rafelt, Suzanne, Rajagopalan, Ramakrishnan, Romaine, Simon P.R., Schork, Nicholas J., Shaffer, Jonathan, Shen, Haiqing, Smith, Erin N., Tischfield, Sam E., van der Most, Peter J., van Vliet-Ostaptchouk, Jana V., Verweij, Niek, Volcik, Kelly A., Zhang, Li, Bailey, Kent R., Bailey, Kristian M., Bauer, Florianne, Boer, Jolanda M.A., Braund, Peter S., Burt, Amber, Burton, Paul R., Buxbaum, Sarah G., Chen, Wei, Cooper-DeHoff, Rhonda M., Cupples, L. Adrienne, deJong, Jonas S., Delles, Christian, Duggan, David, Fornage, Myriam, Furlong, Clement E., Glazer, Nicole, Gums, John G., Hastie, Claire, Holmes, Michael V., Illig, Thomas, Kirkland, Susan A., Kivimaki, Mika, Klein, Ronald, Klein, Barbara E., Kooperberg, Charles, Kottke-Marchant, Kandice, Kumari, Meena, LaCroix, Andrea Z., Mallela, Laya, Murugesan, Gurunathan, Ordovas, Jose, Ouwehand, Willem H., Post, Wendy S., Saxena, Richa, Scharnagl, Hubert, Schreiner, Pamela J., Shah, Tina, Shields, Denis C., Shimbo, Daichi, Srinivasan, Sathanur R., Stolk, Ronald P., Swerdlow, Daniel I., Taylor, Herman A., Topol, Eric J., Toskala, Elina, van Pelt, Joost L., van Setten, Jessica, Yusuf, Salim, Whittaker, John C., Zwinderman, A.H., Anand, Sonia S., Balmforth, Anthony J., Berenson, Gerald S., Bezzina, Connie R., Boehm, Bernhard O., Boerwinkle, Eric, Casas, Juan P., Caulfield, Mark J., Clarke, Robert, Connell, John M., Cruickshanks, Karen J., Davidson, Karina W., Day, Ian N.M., de Bakker, Paul I.W., Doevendans, Pieter A., Dominiczak, Anna F., Hall, Alistair S., Hartman, Catharina A., Hengstenberg, Christian, Hillege, Hans L., Hofker, Marten H., Humphries, Steve E., Jarvik, Gail P., Johnson, Julie A., Kaess, Bernhard M., Kathiresan, Sekar, Koenig, Wolfgang, Lawlor, Debbie A., März, Winfried, Melander, Olle, Mitchell, Braxton D., Montgomery, Grant W., Munroe, Patricia B., Murray, Sarah S., Newhouse, Stephen J., Onland-Moret, N. Charlotte, Poulter, Neil, Psaty, Bruce, Redline, Susan, Rich, Stephen S., Rotter, Jerome I., Schunkert, Heribert, Sever, Peter, Shuldiner, Alan R., Silverstein, Roy L., Stanton, Alice, Thorand, Barbara, Trip, Mieke D., Tsai, Michael Y., van der Harst, Pim, van der Schoot, Ellen, van der Schouw, Yvonne T., Verschuren, W.M. Monique, Watkins, Hugh, Wilde, Arthur A.M., Wolffenbuttel, Bruce H.R., Whitfield, John B., Hovingh, G. Kees, Ballantyne, Christie M., Wijmenga, Cisca, Reilly, Muredach P., Martin, Nicholas G., Wilson, James G., Rader, Daniel J., Samani, Nilesh J., Reiner, Alex P., Hegele, Robert A., Kastelein, John J.P., Hingorani, Aroon D., Talmud, Philippa J., Hakonarson, Hakon, Elbers, Clara C., Keating, Brendan J., Drenos, Fotios
Publicado em 2012