Genetics of cardiac arrhythmias

Por Wilde, Arthur A M, Bezzina, Connie R
Publicado em 2005

Next-Generation Sequencing in Post-mortem Genetic Testing of Young Sudden Cardiac Death Cases

Por Lahrouchi, Najim, Behr, Elijah R., Bezzina, Connie R.
Publicado no Front Cardiovasc Med (2016)

Genetic Basis of Ventricular Arrhythmias

Por Pazoki, Raha, Wilde, Arthur A. M., Bezzina, Connie R.
Publicado em 2010

Induced pluripotent stem cell derived cardiomyocytes as models for cardiac arrhythmias

Por Hoekstra, Maaike, Mummery, Christine L., Wilde, Arthur A. M., Bezzina, Connie R., Verkerk, Arie O.
Publicado em 2012

hiPSC-derived cardiomyocytes from Brugada Syndrome patients without identified mutations do not exhibit clear cellular electrophysiological abnormalities

Por Veerman, Christiaan C., Mengarelli, Isabella, Guan, Kaomei, Stauske, Michael, Barc, Julien, Tan, Hanno L., Wilde, Arthur A. M., Verkerk, Arie O., Bezzina, Connie R.
Publicado no Sci Rep (2016)

A Heterozygous Deletion Mutation in the Cardiac Sodium Channel Gene SCN5A with Loss- and Gain-of-Function Characteristics Manifests as Isolated Conduction Disease, without Signs of...

Por Zumhagen, Sven, Veldkamp, Marieke W., Stallmeyer, Birgit, Baartscheer, Antonius, Eckardt, Lars, Paul, Matthias, Remme, Carol Ann, Bhuiyan, Zahurul A., Bezzina, Connie R., Schulze-Bahr, Eric
Publicado em 2013

SNPs Identified as Modulators of ECG Traits in the General Population Do Not Markedly Affect ECG Traits during Acute Myocardial Infarction nor Ventricular Fibrillation Risk in This...

Por Pazoki, Raha, de Jong, Jonas S.S.G., Marsman, Roos F., Bruinsma, Nienke, Dekker, Lukas R. C., Wilde, Arthur A. M., Bezzina, Connie R., Tanck, Michael W. T.
Publicado em 2013

Dissection of a Quantitative Trait Locus for PR Interval Duration Identifies Tnni3k as a Novel Modulator of Cardiac Conduction

Por Lodder, Elisabeth M., Scicluna, Brendon P., Milano, Annalisa, Sun, Albert Y., Tang, Hao, Remme, Carol Ann, Moerland, Perry D., Tanck, Michael W. T., Pitt, Geoffrey S., Marchuk, Douglas A., Bezzina, Connie R.
Publicado em 2012

The role of renin–angiotensin–aldosterone system polymorphisms in phenotypic expression of MYBPC3-related hypertrophic cardiomyopathy

Por Kolder, Iris CRM, Michels, Michelle, Christiaans, Imke, Ten Cate, Folkert J, Majoor-Krakauer, Danielle, Danser, Alexander HJ, Lekanne Deprez, Robert H, Tanck, Michael WT, Wilde, Arthur AM, Bezzina, Connie R, Dooijes, Dennis
Publicado em 2012

Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer

Por van den Boogaard, Malou, Wong, L.Y. Elaine, Tessadori, Federico, Bakker, Martijn L., Dreizehnter, Lisa K., Wakker, Vincent, Bezzina, Connie R., ‘t Hoen, Peter A.C., Bakkers, Jeroen, Barnett, Phil, Christoffels, Vincent M.
Publicado em 2012

Haplotype-Sharing Analysis Implicates Chromosome 7q36 Harboring DPP6 in Familial Idiopathic Ventricular Fibrillation

Por Alders, Marielle, Koopmann, Tamara T., Christiaans, Imke, Postema, Pieter G., Beekman, Leander, Tanck, Michael W.T., Zeppenfeld, Katja, Loh, Peter, Koch, Karel T., Demolombe, Sophie, Mannens, Marcel M.A.M., Bezzina, Connie R., Wilde, Arthur A.M.
Publicado em 2009

Fever-induced QTc prolongation and ventricular arrhythmias in individuals with type 2 congenital long QT syndrome

Por Amin, Ahmad S., Herfst, Lucas J., Delisle, Brian P., Klemens, Christine A., Rook, Martin B., Bezzina, Connie R., Underkofler, Heather A.S., Holzem, Katherine M., Ruijter, Jan M., Tan, Hanno L., January, Craig T., Wilde, Arthur A.M.
Publicado em 2008

Genome-Wide Identification of Expression Quantitative Trait Loci (eQTLs) in Human Heart

Por Koopmann, Tamara T., Adriaens, Michiel E., Moerland, Perry D., Marsman, Roos F., Westerveld, Margriet L., Lal, Sean, Zhang, Taifang, Simmons, Christine Q., Baczko, Istvan, dos Remedios, Cristobal, Bishopric, Nanette H., Varro, Andras, George, Alfred L., Lodder, Elisabeth M., Bezzina, Connie R.
Publicado em 2014

Sodium channel β1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humans

Por Watanabe, Hiroshi, Koopmann, Tamara T., Le Scouarnec, Solena, Yang, Tao, Ingram, Christiana R., Schott, Jean-Jacques, Demolombe, Sophie, Probst, Vincent, Anselme, Frédéric, Escande, Denis, Wiesfeld, Ans C.P., Pfeufer, Arne, Kääb, Stefan, Wichmann, H.-Erich, Hasdemir, Can, Aizawa, Yoshifusa, Wilde, Arthur A.M., Roden, Dan M., Bezzina, Connie R.
Publicado em 2008

Myocyte necrosis underlies progressive myocardial dystrophy in mouse dsg2-related arrhythmogenic right ventricular cardiomyopathy

Por Pilichou, Kalliopi, Remme, Carol Ann, Basso, Cristina, Campian, Maria E., Rizzo, Stefania, Barnett, Phil, Scicluna, Brendon P., Bauce, Barbara, van den Hoff, Maurice J.B., de Bakker, Jacques M.T., Tan, Hanno L., Valente, Marialuisa, Nava, Andrea, Wilde, Arthur A.M., Moorman, Antoon F.M., Thiene, Gaetano, Bezzina, Connie R.
Publicado em 2009

A Connexin 40 Mutation Associated with a Malignant Variant of Progressive Familial Heart Block Type-1

Por Makita, Naomasa, Seki, Akiko, Sumitomo, Naokata, Chkourko, Halina, Fukuhara, Shigetomo, Watanabe, Hiroshi, Shimizu, Wataru, Bezzina, Connie R., Hasdemir, Can, Mugishima, Hideo, Makiyama, Takeru, Baruteau, Alban, Baron, Estelle, Horie, Minoru, Hagiwara, Nobuhisa, Wilde, Arthur A.M., Probst, Vincent, Le Marec, Hervé, Roden, Dan M., Mochizuki, Naoki, Schott, Jean-Jacques, Delmar, Mario
Publicado no Circ Arrhythm Electrophysiol (2012)

Identification of FOXP1 Deletions in Three Unrelated Patients with Mental Retardation and Significant Speech and Language Deficits

Por Horn, Denise, Kapeller, Johannes, Rivera-Brugués, Núria, Moog, Ute, Lorenz-Depiereux, Bettina, Eck, Sebastian, Hempel, Maja, Wagenstaller, Janine, Gawthrope, Alex, Monaco, Anthony P, Bonin, Michael, Riess, Olaf, Wohlleber, Eva, Illig, Thomas, Bezzina, Connie R, Franke, Andre, Spranger, Stephanie, Villavicencio-Lorini, Pablo, Seifert, Wenke, Rosenfeld, Jochen, Klopocki, Eva, Rappold, Gudrun A, Strom, Tim M
Publicado em 2010

Variants in the 3′ untranslated region of the KCNQ1-encoded K(v)7.1 potassium channel modify disease severity in patients with type 1 long QT syndrome in an allele-specific manner...

Por Amin, Ahmad S., Giudicessi, John R., Tijsen, Anke J., Spanjaart, Anne M., Reckman, Yolan J., Klemens, Christine A., Tanck, Michael W., Kapplinger, Jamie D., Hofman, Nynke, Sinner, Moritz F., Müller, Martina, Wijnen, Wino J., Tan, Hanno L., Bezzina, Connie R., Creemers, Esther E., Wilde, Arthur A. M., Ackerman, Michael J., Pinto, Yigal M.
Publicado em 2012

Coxsackie and adenovirus receptor (CAR) is a modifier of cardiac conduction and arrhythmia vulnerability in the setting of myocardial ischemia

Por Marsman, Roos F.J., Bezzina, Connie R., Freiberg, Fabian, Verkerk, Arie O., Adriaens, Michiel E., Podliesna, Svitlana, Chen, Chen, Purfürst, Bettina, Spallek, Bastian, Koopmann, Tamara T., Baczko, Istvan, dos Remedios, Cristobal G., George, Alfred L., Bishopric, Nanette H., Lodder, Elisabeth M., de Bakker, Jacques M.T., Fischer, Robert, Coronel, Ruben, Wilde, Arthur A.M., Gotthardt, Michael, Remme, Carol Ann
Publicado em 2013

Analysis for Genetic Modifiers of Disease Severity in Patients With Long-QT Syndrome Type 2

Por Kolder, Iris C.R.M., Tanck, Michael W.T., Postema, Pieter G., Barc, Julien, Sinner, Moritz F., Zumhagen, Sven, Husemann, Anja, Stallmeyer, Birgit, Koopmann, Tamara T., Hofman, Nynke, Pfeufer, Arne, Lichtner, Peter, Meitinger, Thomas, Beckmann, Britt M., Myerburg, Robert J., Bishopric, Nanette H., Roden, Dan M., Kääb, Stefan, Wilde, Arthur A.M., Schott, Jean-Jacques, Schulze-Bahr, Eric, Bezzina, Connie R.
Publicado no Circ Cardiovasc Genet (2015)