Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer

The contraction pattern of the heart relies on the activation and conduction of the electrical impulse. Perturbations of cardiac conduction have been associated with congenital and acquired arrhythmias as well as cardiac arrest. The pattern of conduction depends on the regulation of heterogeneous ge...

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Detalhes bibliográficos
Main Authors: van den Boogaard, Malou, Wong, L.Y. Elaine, Tessadori, Federico, Bakker, Martijn L., Dreizehnter, Lisa K., Wakker, Vincent, Bezzina, Connie R., ‘t Hoen, Peter A.C., Bakkers, Jeroen, Barnett, Phil, Christoffels, Vincent M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386824/
https://ncbi.nlm.nih.gov/pubmed/22706305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62613
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