T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system

Genome-wide association studies have identified noncoding variants near TBX3 that are associated with PR interval and QRS duration, suggesting that subtle changes in TBX3 expression affect atrioventricular conduction system function. To explore whether and to what extent the atrioventricular conduct...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Mohan, Rajiv A., Bosada, Fernanda M., van Weerd, Jan H., van Duijvenboden, Karel, Wang, Jianan, Mommersteeg, Mathilda T. M., Hooijkaas, Ingeborg B., Wakker, Vincent, de Gier-de Vries, Corrie, Coronel, Ruben, Boink, Gerard J. J., Bakkers, Jeroen, Barnett, Phil, Boukens, Bas J., Christoffels, Vincent M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414162/
https://ncbi.nlm.nih.gov/pubmed/32675240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1919379117
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