Genome-Wide Analysis Identifies an Essential Human TBX3 Pacemaker Enhancer.

RATIONALE: The development and function of the pacemaker cardiomyocytes of the sinoatrial node (SAN), the leading pacemaker of the heart, are tightly controlled by a conserved network of transcription factors, including TBX3, ISL1 and SHOX2. Yet, the regulatory DNA elements (REs) controlling target...

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Publicado no:Circ Res
Main Authors: van Eif, Vincent W.W., Protze, Stephanie, Bosada, Fernanda M., Yuan, Xuefei, Sinha, Tanvi, van Duijvenboden, Karel, Ernault, Auriane C., Mohan, Rajiv A., Wakker, Vincent, de Gier-de Vries, Corrie, Hooijkaas, Ingeborg B., Wilson, Michael D., Verkerk, Arie O., Bakkers, Jeroen, Boukens, Bastiaan J., Black, Brian L., Scott, Ian C., Christoffels, Vincent M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8153223/
https://ncbi.nlm.nih.gov/pubmed/33040635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.120.317054
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