T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system

Genome-wide association studies have identified noncoding variants near TBX3 that are associated with PR interval and QRS duration, suggesting that subtle changes in TBX3 expression affect atrioventricular conduction system function. To explore whether and to what extent the atrioventricular conduct...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Mohan, Rajiv A., Bosada, Fernanda M., van Weerd, Jan H., van Duijvenboden, Karel, Wang, Jianan, Mommersteeg, Mathilda T. M., Hooijkaas, Ingeborg B., Wakker, Vincent, de Gier-de Vries, Corrie, Coronel, Ruben, Boink, Gerard J. J., Bakkers, Jeroen, Barnett, Phil, Boukens, Bas J., Christoffels, Vincent M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414162/
https://ncbi.nlm.nih.gov/pubmed/32675240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1919379117
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