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GATA-dependent regulatory switches establish atrioventricular canal specificity during heart development
The embryonic vertebrate heart tube develops an atrioventricular canal that divides the atrial and ventricular chambers, forms atrioventricular conduction tissue and organizes valve development. Here we assess the transcriptional mechanism underlying this localized differentiation process. We show t...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Pub. Group
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4015328/ https://ncbi.nlm.nih.gov/pubmed/24770533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4680 |
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