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GATA-dependent regulatory switches establish atrioventricular canal specificity during heart development

The embryonic vertebrate heart tube develops an atrioventricular canal that divides the atrial and ventricular chambers, forms atrioventricular conduction tissue and organizes valve development. Here we assess the transcriptional mechanism underlying this localized differentiation process. We show t...

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Autors principals: Stefanovic, Sonia, Barnett, Phil, van Duijvenboden, Karel, Weber, David, Gessler, Manfred, Christoffels, Vincent M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015328/
https://ncbi.nlm.nih.gov/pubmed/24770533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4680
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