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GATA-dependent regulatory switches establish atrioventricular canal specificity during heart development

The embryonic vertebrate heart tube develops an atrioventricular canal that divides the atrial and ventricular chambers, forms atrioventricular conduction tissue and organizes valve development. Here we assess the transcriptional mechanism underlying this localized differentiation process. We show t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Stefanovic, Sonia, Barnett, Phil, van Duijvenboden, Karel, Weber, David, Gessler, Manfred, Christoffels, Vincent M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015328/
https://ncbi.nlm.nih.gov/pubmed/24770533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4680
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