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Developmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factors

Mutations in Notch2, Jagged1 or homologs of the Hairy-related transcriptional repressor Hey2 cause congenital malformations involving the non-chamber atrioventricular canal (AVC) and inner curvature (IC) regions of the heart, but the underlying mechanisms have not been investigated. By manipulating...

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Detalhes bibliográficos
Main Authors: Rutenberg, Joshua B., Fischer, Andreas, Jia, Haibo, Gessler, Manfred, Zhong, Tao P., Mercola, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619037/
https://ncbi.nlm.nih.gov/pubmed/17021042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.02607
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