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The Notch target genes Hey1 and Hey2 are required for embryonic vascular development
The Delta–Notch signaling pathway plays a central role in the development of most vertebrate organs. The Hey family of bHLH transcription factors are direct targets of Notch signaling. Loss of Hey2 in the mouse leads to cardiac defects with high postnatal lethality. We have now generated a mouse Hey...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC395849/ https://ncbi.nlm.nih.gov/pubmed/15107403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.291004 |
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