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Serum Induces Transcription of Hey1 and Hey2 Genes by Alk1 but Not Notch Signaling in Endothelial Cells

The transcriptional repressors Hey1 and Hey2 are primary target genes of Notch signaling in the cardiovascular system and induction of Hey gene expression is often interpreted as activation of Notch signaling. Here we report that treatment of primary human endothelial cells with serum or fresh growt...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wöltje, Kerstin, Jabs, Markus, Fischer, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370690/
https://ncbi.nlm.nih.gov/pubmed/25799559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120547
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