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Serum Induces Transcription of Hey1 and Hey2 Genes by Alk1 but Not Notch Signaling in Endothelial Cells

The transcriptional repressors Hey1 and Hey2 are primary target genes of Notch signaling in the cardiovascular system and induction of Hey gene expression is often interpreted as activation of Notch signaling. Here we report that treatment of primary human endothelial cells with serum or fresh growt...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Wöltje, Kerstin, Jabs, Markus, Fischer, Andreas
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370690/
https://ncbi.nlm.nih.gov/pubmed/25799559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120547
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