Hey Basic Helix-Loop-Helix Transcription Factors Are Repressors of GATA4 and GATA6 and Restrict Expression of the GATA Target Gene ANF in Fetal Hearts

The Hey basic helix-loop-helix transcription factors are downstream effectors of Notch signaling in the cardiovascular system. Mice lacking Hey2 develop cardiac hypertrophy, often associated with congenital heart defects, whereas combined Hey1/Hey2 deficiency leads to severe vascular defects and emb...

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Autori principali: Fischer, Andreas, Klattig, Jürgen, Kneitz, Burkhard, Diez, Holger, Maier, Manfred, Holtmann, Bettina, Englert, Christoph, Gessler, Manfred
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
Soggetti:
Gene Expression
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265774/
https://ncbi.nlm.nih.gov/pubmed/16199874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.20.8960-8970.2005
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